| 100% | KENANTHOMPSON | 13 | "Saturday Night Live" comedian who hosted the Nickelodeon Kids' Choice Awards in 2021: 2 wds. |
| 82% | KENANTHOMPSON | 13 | "Saturday Night Live" comedian who hosted the People's Choice Awards in 2021 and 2022: 2 wds. |
| 67% | DJKHALED | 8 | "Higher" performer who hosted the Nickelodeon Kids' Choice Awards in 2019: 2 wds. |
| 66% | JOHNCENA | 8 | Professional wrestler and actor who hosted the Nickelodeon Kids' Choice Awards in 2017 and 2018: 2 wds. |
| 53% | LESLIEJONES | 11 | "Saturday Night Live" star who hosted the 2017 BET Awards: 2 wds. |
| 52% | NORMMACDONALD | 13 | "Saturday Night Live" comedian who voiced the dog Lucky in "Dr. Dolittle": 2 wds. |
| 52% | LESLIEJONES | 11 | Former "Saturday Night Live" comedian who hosts the prime-time game show "Supermarket Sweep": 2 wds. |
| 51% | JOELMCHALE | 10 | "Community" actor who hosted the People's Choice Awards in 2017: 2 wds. |
| 51% | GEORGECARLIN | 12 | Comedian who hosted the first episode of "Saturday Night Live" on October 11, 1975 (2 wds.) |
| 50% | DEMILOVATO | 10 | "Sorry Not Sorry" singer who hosted the People's Choice Awards in 2020: 2 wds. |
| 49% | JENNYSLATE | 10 | Former "Saturday Night Live" comedian who voices the Pomeranian Gidget in "The Secret Life of Pets" films: 2 wds. |
| 47% | TRACYMORGAN | 11 | Former "Saturday Night Live" cast member who hosted the 2019 ESPY Awards ceremony (2 wds.) |
| 46% | AMYPOEHLER | 10 | "Saturday Night Live" comedian who went on to star in 24-Across and 36-/42-Across: 2 wds. |
| 46% | SETHMEYERS | 10 | "Late Night" host who hosted the ESPY Awards in 2010 and 2011: 2 wds. |
| 45% | KENANTHOMPSON | 13 | Comedian and "Saturday Night Live" cast member who voices Gus the beaver in 43-Across (2 wds.) |
| 45% | GEORGEFOREMAN | 13 | Boxer who hosted "Saturday Night Live" in 1994: 2 wds. |
| 45% | LORNEMICHAELS | 13 | "Saturday Night Live" producer who was inducted into the Television Hall of Fame in 1999: 2 wds. |
| 44% | JOEMONTANA | 10 | 49ers player who hosted "Saturday Night Live" in 1987: 2 wds. |
| 44% | DEREKJETER | 10 | Yankees player who hosted "Saturday Night Live" in 2001: 2 wds. |
| 44% | ELONMUSK | 8 | SpaceX founder who hosted "Saturday Night Live" in May: 2 wds. |
| 44% | CHRISROCK | 9 | "Saturday Night Live" cast member (1990-1993) who voiced the zebra Marty in the "Madagascar" movies: 2 wds. |
| 43% | ROBSCHNEIDER | 12 | Former "Saturday Night Live" comedian who was the Hamster on season 6 of "The Masked Singer": 2 wds. |
| 43% | JAMIEFOXX | 9 | "Django Unchained" star who hosted the ESPY Awards in 2003 and 2004: 2 wds. |
| 42% | WILLFERRELL | 11 | "Elf" actor and "Saturday Night Live" star who won the Mark Twain Prize for American Humor in 2011: 2 wds. |
| 42% | ELTONJOHN | 9 | "Rocket Man" singer who hosted and performed on "Saturday Night Live" in 2011: 2 wds. |
| 42% | LORNEMICHAELS | 13 | "Saturday Night Live" creator who was awarded the Mark Twain Prize for American Humor (2 wds.) |
| 42% | KATEMCKINNON | 12 | "Saturday Night Live" cast member who voices Squeeks the Mouse on PBS Kids' "Nature Cat" (2 wds.) |
| 42% | PEYTONMANNING | 13 | Pro Football Hall of Fame quarterback who hosted "Saturday Night Live" in 2007, the same year he was named Super Bowl MVP (2 wds.) |
| 41% | MARCMARON | 9 | Comedian who hosts the "WTF" podcast: 2 wds. |
| 41% | FREDARMISEN | 11 | Former "Saturday Night Live" comedian who cocreated and frequently appears on 34-Across: 2 wds. |