| 100% | JADEPETTYJOHN | 13 | "School of Rock" and "Little Fires Everywhere" actress who plays a kidnapped teen on 1-Across/65-Across (2 wds.) |
| 55% | BRIANGERAGHTY | 13 | "Chicago Med" and "Chicago Fire" actor who plays a long-haul trucker on 1-Across/65-Across (2 wds.) |
| 52% | RYANPHILLIPPE | 13 | "Damages" and "Shooter" actor who plays a former cop on 1-Across/65-Across (2 wds.) |
| 49% | MARLEEMATLIN | 12 | "CODA" actress who played a deaf employee at the school in "Children of a Lesser God": 2 wds. |
| 48% | KATEMARA | 8 | "House of Cards" actress who plays high school instructor Claire Wilson on 14-Across: 2 wds. |
| 46% | DANADELANY | 10 | "China Beach" actress who played a medical examiner on "Body of Proof": 2 wds. |
| 46% | PIPERLAURIE | 11 | "Carrie" actress who played 27-Across's mother in "Children of a Lesser God": 2 wds. |
| 45% | ALLYSHEEDY | 10 | Actress who, in 1985, played a high school outcast in "The Breakfast Club" and an aspiring architect in "St. Elmo's Fire": 2 wds. |
| 45% | ELIZABETHOLSEN | 14 | Actress who plays a powerful witch in Marvel's "Avengers" films and on 44-Across (2 wds.) |
| 44% | EDWINAFINDLEY | 13 | "The Wire" and "Treme" actress who plays a White House butler on "The Residence": 2 wds. |
| 44% | DAMIANMCGINTY | 13 | Irish singer who played Rory Flanagan on "Glee" and was a member of 32-Across: 2 wds. |
| 43% | KATIELEUNG | 10 | "Harry Potter and the Goblet of Fire" actress who plays Fan in "The Foreigner": 2 wds. |
| 43% | HOPEDAVIS | 9 | "Wayward Pines" actress who plays the wife of a mob boss on 54-Across (2 wds.) |
| 43% | WHOOPIGOLDBERG | 14 | "Sister Act" actress who played God in the films "A Little Bit of Heaven" and "It's a Very Merry Muppet Christmas Movie" (2 wds.) |
| 43% | CHRISPERFETTI | 13 | "Looking" actor who plays a history teacher and ally of 15-Across: 2 wds. |
| 42% | SONJASOHN | 9 | "Body of Proof" actress who plays GBI Deputy Director Amanda Wagner on 16-Across: 2 wds. |
| 42% | LISAANNWALTER | 13 | "Bruce Almighty" actress who plays a teacher and ally of 15-Across: 3 wds. |
| 42% | AMYPOEHLER | 10 | Actress who played the role of Leslie Knope in "Parks and Recreation", a role she is best-known for: 2 wds. |
| 42% | EVAGREEN | 8 | "300: Rise of an Empire" actress who played Vanessa Ives on 21-Across: 2 wds. |
| 41% | ALEXISBLEDEL | 12 | "The Sisterhood of the Traveling Pants" actress who played daughter Rory on 14-Across: 2 wds. |
| 41% | SASHAALEXANDER | 14 | "NCIS" actress who played a medical examiner on "Rizzoli & Isles": 2 wds. |
| 41% | ANTONIATHOMAS | 13 | Actress who plays Shaun's friend and fellow resident Claire on 15-Across: 2 wds. |
| 41% | CYNTHIANIXON | 12 | "Sex and the City" actress who plays socialite Ada Brook on 44-Across (2 wds.) |
| 41% | JUDDNELSON | 10 | Actor who played a high school delinquent in "The Breakfast Club" and a yuppie politician in "St. Elmo's Fire": 2 wds. |
| 41% | EMILIOESTEVEZ | 13 | Actor who played a high school jock in "The Breakfast Club" and a law student in "St. Elmo's Fire": 2 wds. |
| 41% | WILLIAMHURT | 11 | "Broadcast News" actor (1950-2022) who played a speech teacher at a deaf school in "Children of a Lesser God": 2 wds. |
| 41% | RASHIDAJONES | 12 | Actress who played Ann Perkins on "Parks and Recreation": 2 wds. |
| 41% | BARBARAEDEN | 11 | Actress who played Jeannie on "I Dream of Jeannie": 2 wds. |
| 41% | LISAWHELCHEL | 12 | Actress who played Blair on "The Facts of Life": 2 wds. |
| 41% | KIMFIELDS | 9 | Actress who played Tootie on "The Facts of Life": 2 wds. |