| 100% | LARRYDAVID | 10 | "Seinfeld" co-creator who plays a fictionalized version of himself on "Curb Your Enthusiasm" (2 wds.) |
| 85% | RICHARDLEWIS | 12 | Stand-up comedian who plays a fictionalized version of himself on "Curb Your Enthusiasm" (2 wds.) |
| 75% | WANDASYKES | 10 | Stand-up comedian who plays a fictionalized version of herself on "Curb Your Enthusiasm" (2 wds.) |
| 56% | JERRYSEINFELD | 13 | Comedian who played a fictional version of himself on a sitcom about "nothing" (2 wds.) |
| 50% | LARRYDAVID | 10 | Actor and comedian who created HBO's comedy series "Curb Your Enthusiasm" and stars in it as a fictionalized version of himself: 2 wds. |
| 47% | ESAIMORALES | 11 | "NYPD Blue" actor who plays a waiter who may have committed credit card fraud on Season 10 of "Curb Your Enthusiasm" (2 wds.) |
| 46% | WILLSMITH | 9 | Actor who starred as a fictionalized version of himself in the hit TV series "The Fresh Prince of Bel-Air": 2 wds. |
| 46% | NYE | 3 | "Science Guy" Bill who plays a fictional version of himself on "Blindspot" |
| 44% | PATRICKHARRIS | 13 | Neil ___, actor who made a cameo in "Harold & Kumar go to White Castle" by playing a fictionalized version of himself: 2 wds. |
| 43% | DANADELANY | 10 | "China Beach" actress who played a medical examiner on "Body of Proof": 2 wds. |
| 43% | RICHARDKIND | 11 | "Curb Your Enthusiasm" actor who played press secretary Paul Lassiter on 45-Across (2 wds.) |
| 41% | CARLOSVALDES | 12 | Actor who plays Cisco Ramon on "The Flash" which is a part of the Arrowverse: 2 wds. |
| 41% | GLENNHOWERTON | 13 | "It's Always Sunny in Philadelphia" star who played a co-CEO of Research in Motion in 2023's "BlackBerry": 2 wds. |
| 40% | SUSIEESSMAN | 11 | Actress who plays the foul-mouthed wife of the main character's manager Jeff on "Curb Your Enthusiasm": 2 wds. |
| 40% | LARRYDAVID | 10 | "Curb Your Enthusiasm" star who gave his Prius to a medical student in 2006: 2 wds. |
| 40% | VINCEVAUGHN | 11 | "True Detective" actor who plays a friend who knows an inventor who can help Larry in Season 10 of "Curb Your Enthusiasm" (2 wds.) |
| 40% | CHERYLHINES | 11 | Actress who plays the main character's ex-wife on "Curb Your Enthusiasm": 2 wds. |
| 39% | TRACEYULLMAN | 12 | "Into the Woods" actress who played Princess Winnifred in the 2005 made-for-TV version of "Once Upon a Mattress": 2 wds. |
| 39% | LAURIEMETCALF | 13 | Actress whose real-life daughter played a younger version of her character on "Roseanne": 2 wds. |
| 39% | HOPEDAVIS | 9 | "Wayward Pines" actress who plays the wife of a mob boss on 54-Across (2 wds.) |
| 38% | JAMESBROLIN | 11 | Actor who played a physician on 28-Across: 2 wds. |
| 38% | SASHEERZAMATA | 13 | 30-Down actress who plays a journalist on "Woke": 2 wds. |
| 38% | SASHAALEXANDER | 14 | "NCIS" actress who played a medical examiner on "Rizzoli & Isles": 2 wds. |
| 38% | WILLIAMSHATNER | 14 | "Star Trek" star who played a murderous actor on "Columbo": 2 wds. |
| 38% | EDDIEALBERT | 11 | "Green Acres" star who played a murderous general on "Columbo": 2 wds. |
| 37% | REBAMCENTIRE | 12 | Grammy-winning country star who plays a singer on 32-Across: 2 wds. |
| 37% | MARSHAMASON | 11 | "The Goodbye Girl" actress who played a grandma on "The Middle": 2 wds. |
| 37% | EDWINAFINDLEY | 13 | "The Wire" and "Treme" actress who plays a White House butler on "The Residence": 2 wds. |
| 37% | JOHNNYDEPP | 10 | "Black Mass" actor who plays a pirate in the "Pirates of the Caribbean" films: 2 wds. |
| 37% | ZOESALDANA | 10 | "Avatar" actress who played a pirate in the first "Pirates of the Caribbean" film: 2 wds. |