| 100% | MICHAELONTKEAN | 14 | "Slap Shot" actor who played Sheriff Harry S. Truman on "Twin Peaks": 2 wds. |
| 52% | GARYOLDMAN | 10 | "Slow Horses" actor who plays Harry S. Truman in "Oppenheimer" (2 wds.) |
| 51% | KYLEMACLACHLAN | 14 | "Twin Peaks" actor who plays Lucy's father Hank on "Fallout": 2 wds. |
| 50% | TEDDANSON | 9 | "Cheers" actor who played Sheriff Hank Larsson on season 2 of "Fargo": 2 wds. |
| 49% | KYLEMACLACHLAN | 14 | "Portlandia" actor who played FBI Special Agent Dale Cooper on "Twin Peaks": 2 wds. |
| 46% | BOBDENVER | 9 | Actor who played Gilligan on "Gilligan's Island": 2 wds. |
| 46% | COREYREYNOLDS | 13 | "The Closer" actor who plays Sheriff Mike Thompson on 50-Across (2 wds.) |
| 46% | SYDNEYPOLLACK | 13 | Actor who plays Will Truman's father on "Will & Grace" (2 wds.) |
| 46% | GREGORYHINES | 12 | Actor who plays Will Truman's boss on "Will & Grace" (2 wds.) |
| 46% | DEANCAIN | 8 | Actor who played Superman on TV's "Lois & Clark": 2 wds. |
| 46% | JIMBACKUS | 9 | Actor who played Thurston Howell III on "Gilligan's Island": 2 wds. |
| 45% | ADAMGOLDBERG | 12 | "Saving Private Ryan" actor who plays hacker Harry Keshegian on 14-Across: 2 wds. |
| 45% | RICHARDSCHIFF | 13 | Actor who plays Shaun's mentor Aaron Glassman on 15-Across: 2 wds. |
| 45% | ALANTUDYK | 9 | "Firefly" actor who plays Harry Vanderspeigle on 50-Across (2 wds.) |
| 45% | MARTINFREEMAN | 13 | "The Hobbit" actor who plays Dr. Watson on the BBC's "Sherlock": 2 wds. |
| 45% | TITUSWELLIVER | 13 | "Sons of Anarchy" actor who plays Harry Bosch on "Bosch" (2 wds.) |
| 44% | JOSHUAJACKSON | 13 | Actor who played Pacey on the 1998-2003 teen drama "Dawson's Creek": 2 wds. |
| 44% | RYANGOSLING | 11 | "Gangster Squad" actor who played Hercules on TV's "Young Hercules": 2 wds. |
| 44% | HUGHLAURIE | 10 | British actor who played American Gregory House on Fox's "House": 2 wds. |
| 44% | MADSMIKKELSEN | 13 | "Casino Royale" actor who plays Hannibal Lecter on NBC's "Hannibal": 2 wds. |
| 44% | BLAKEANDERSON | 13 | "Workaholics" actor who plays one of Keef's roommates on "Woke": 2 wds. |
| 44% | TOMSTURRIDGE | 12 | "Velvet Buzzsaw" actor who plays Dream on Netflix's "The Sandman": 2 wds. |
| 44% | GARYCOOPER | 10 | Actor who played sheriff Will Kane in "High Noon": 2 wds. |
| 44% | JEFFREYTAMBOR | 13 | "Transparent" actor who played Michael Bluth's father George on "Arrested Development": 2 wds. |
| 44% | BENJAMINBRATT | 13 | "Law & Order" actor who played Gloria's ex-husband Javier on "Modern Family": 2 wds. |
| 44% | RONLEIBMAN | 10 | "Norma Rae" actor who played Rachel's father, Dr. Leonard Green, on "Friends": 2 wds. |
| 44% | HUGHDANCY | 9 | "Confessions of a Shopaholic" actor who plays Will Graham on NBC's "Hannibal": 2 wds. |
| 44% | ANDREWLINCOLN | 13 | British actor who plays American Rick Grimes on AMC's "The Walking Dead": 2 wds. |
| 44% | CLANCYBROWN | 11 | "The Shawshank Redemption" actor who plays Rich Brink on Amazon's "Gen V": 2 wds. |
| 44% | ERICWINTER | 10 | "The Mentalist" actor who plays Sergeant Tim Bradford on ABC's "The Rookie": 2 wds. |