| 100% | JERRYOCONNELL | 13 | "Sliders" actor who voices first officer Jack Ransom on "Star Trek: Lower Decks": 2 wds. |
| 59% | JACKQUAID | 9 | "The Boys" actor who voices ensign Brad Boimler on "Star Trek: Lower Decks": 2 wds. |
| 49% | NOELWELLS | 9 | "Master of None" actress who voices ensign D'Vana Tendi on "Star Trek: Lower Decks": 2 wds. |
| 48% | JACKQUAID | 9 | "Star Trek: Lower Decks" actor who plays newbie vigilante Hughie Campbell on "The Boys": 2 wds. |
| 48% | JERRYOCONNELL | 13 | "Star Trek: Lower Decks" voice actor who is one of "Your Hosts" on "The Real Love Boat" (2 wds.) |
| 40% | PATRICKSTEWART | 14 | Actor who played Captain Jean-Luc Picard on "Star Trek: The Next Generation": 2 wds. |
| 39% | WILWHEATON | 10 | "Star Trek: The Next Generation" actor who voices amnesiac chef Earl Harlan, a character on 15-/51-Across: 2 wds. |
| 39% | SETHGREEN | 9 | Actor who voices Chris Griffin on "Family Guy": 2 wds. |
| 39% | HARRYSHEARER | 12 | Actor who voices Principal Seymour Skinner on "The Simpsons": 2 wds. |
| 38% | STEVENYEUN | 10 | Actor who voices Bo the donkey in the movie "The Star": 2 wds. |
| 38% | TYLERPERRY | 10 | Actor who voices Cyrus the camel in the movie "The Star": 2 wds. |
| 38% | CHRISPARNELL | 12 | Former "SNL" actor who voices Cyril Figgis on "Archer": 2 wds. |
| 38% | RONFUNCHES | 10 | "Undateable" actor who voices King Shark on "Harley Quinn": 2 wds. |
| 38% | TONYHALE | 8 | "Veep" actor who voices Doctor Psycho on "Harley Quinn": 2 wds. |
| 38% | TREYPARKER | 10 | "BASEketball" actor who voices teacher Herbert Garrison on "South Park": 2 wds. |
| 38% | PATTONOSWALT | 12 | "Ratatouille" actor who voices Matthew the Raven on "The Sandman": 2 wds. |
| 38% | BENFELDMAN | 10 | "Superstore" actor who voices Avi Schwooper on "Long Story Short": 2 wds. |
| 37% | MICHAELMADSEN | 13 | "Reservoir Dogs" actor who guest starred as the voice of Kevin Costner on 29-Across (2 wds.) |
| 37% | AVERYBROOKS | 11 | Actor who played Captain Benjamin Sisko on "Star Trek: Deep Space Nine": 2 wds. |
| 37% | WILLIAMSHATNER | 14 | "Star Trek" star who played a murderous actor on "Columbo": 2 wds. |
| 37% | ETHANPECK | 9 | "Star Trek: Discovery" actor who plays Spock on "Strange New Worlds": 2 wds. |
| 37% | JOHNAMOS | 8 | Actor who starred on "Good Times," a Norman Lear sitcom: 2 wds. |
| 37% | SHERMANHEMSLEY | 14 | Actor who starred on "The Jeffersons," a Norman Lear sitcom: 2 wds. |
| 37% | MRT | 3 | Tough actor who starred on "The A-Team": 2 wds. |
| 36% | RYANEGGOLD | 10 | "The Blacklist" actor who currently stars on 25-Across: 2 wds. |
| 36% | CARROLLOCONNOR | 14 | Actor who starred on "All in the Family," a Norman Lear sitcom: 2 wds. |
| 36% | JOHNDIMAGGIO | 12 | Actor who voices the robot Bender on "Futurama" (2 wds.) |
| 36% | ROBERTDUVALL | 12 | "The Godfather" actor who starred in the 1989 miniseries based on 14-Across: 2 wds. |
| 36% | SETHROGEN | 9 | "Pineapple Express" actor who stars as industry head Matt Remick on 15-Across: 2 wds. |
| 36% | AUSTINSTOWELL | 13 | "Bridge of Spies" actor who stars as a young Jethro on "NCIS: Origins": 2 wds. |