| 100% | SHATNER | 7 | "Star Trek" actor William who went to space in 2021 |
| 46% | SHATNER | 7 | Actor William __, played Captain Kirk in Star Trek |
| 46% | SIMULIU | 7 | Kim's Convenience actor who went on to star in the Marvel Cinematic Universe |
| 43% | EVAN | 4 | Actor Peters who's set to star in "Tron: Ares" |
| 42% | TOMMYLEEJONES | 13 | Texas-born former soap actor who went on to star in "Men in Black": 3 wds. |
| 42% | OLIVIAMUNN | 10 | The Daily Show correspondent who went on to star in an X-Men movie |
| 42% | CAGE | 4 | Actor Nicolas who voices Superman in "Teen Titans Go! To the Movies" |
| 42% | DYLAN | 5 | Actor McDermott who starred in the 2018 Fox series "LA to Vegas" |
| 42% | GARN | 4 | Senator Jake who went to space |
| 42% | EVALONGORIA | 11 | Texas-born former soap actress who went on to star in "Desperate Housewives": 2 wds. |
| 42% | IDRISELBA | 9 | Actor who starred in the 2013 bio-pic “Mandela: Long Walk to Freedom” |
| 42% | ANTONRODGERS | 12 | Actor who starred in BBC TV sitcom May to December from 1989-94 |
| 42% | ASA | 3 | ___ Butterfield, actor who starred in the film "The Space Between Us" |
| 41% | ROBINWRIGHT | 11 | Texas-born former soap actress who went on to star in "House of Cards": 2 wds. |
| 41% | DWAYNEJOHNSON | 13 | "Baywatch" actor who stars in "Jumanji: Welcome to the Jungle": 2 wds. |
| 41% | COLMMEANEY | 10 | "Star Trek: Deep Space Nine" actor who plays Bernie Ohls in "Marlowe" (2 wds.) |
| 41% | KEVINHART | 9 | "Jumanji: Welcome to the Jungle" actor who stars in "Night School": 2 wds. |
| 40% | KARLURBAN | 9 | Actor who plays Doctor McCoy in Star Trek remakes |
| 40% | WILLIAM | 7 | ___ Shatner, Canadian actor who starred in "Star Trek" |
| 40% | AMYPOEHLER | 10 | "Saturday Night Live" comedian who went on to star in 24-Across and 36-/42-Across: 2 wds. |
| 40% | GAUNT | 5 | William —, actor who starred as Arthur Crabtree in 1980s BBC TV sitcom No Place Like Home |
| 40% | BRUCEWILLIS | 11 | "A Good Day to Die Hard" actor who stars in 49-Across: 2 wds. |
| 40% | KEVINHART | 9 | "Ride Along 2" actor who stars in "Jumanji: Welcome to the Jungle": 2 wds. |
| 40% | BRANSON | 7 | Richard who flew to the edge of space in 2021 |
| 40% | CHO | 3 | Actor John who plays Sulu in "Star Trek" |
| 40% | PARE | 4 | Actor Michael ___, once a chef in NYC, who starred as Cody in 2008's "Road to Hell" |
| 40% | TYLER | 5 | ___ James Williams, "Criminal Minds: Beyond Borders" actor who stars in "Abbott Elementary" as Gregory Eddie |
| 40% | JACKBLACK | 9 | "Kung Fu Panda 3" actor who stars in "Jumanji: Welcome to the Jungle": 2 wds. |
| 39% | SIMON | 5 | Actor Pegg who plays Scotty in "Star Trek Beyond" |
| 39% | CHO | 3 | Actor John who plays Sulu in "Star Trek Beyond" |