| 100% | WILLIAMSHATNER | 14 | "Star Trek" star who played a murderous actor on "Columbo": 2 wds. |
| 79% | EDDIEALBERT | 11 | "Green Acres" star who played a murderous general on "Columbo": 2 wds. |
| 69% | DICKVANDYKE | 11 | "Diagnosis: Murder" star who played a murderous photographer on "Columbo": 3 wds. |
| 61% | AVERYBROOKS | 11 | Actor who played Captain Benjamin Sisko on "Star Trek: Deep Space Nine": 2 wds. |
| 61% | JAMESBROLIN | 11 | Actor who played a physician on 28-Across: 2 wds. |
| 60% | REBAMCENTIRE | 12 | Grammy-winning country star who plays a singer on 32-Across: 2 wds. |
| 59% | ETHANPECK | 9 | "Star Trek: Discovery" actor who plays Spock on "Strange New Worlds": 2 wds. |
| 59% | BILLYBOB | 8 | With 48-Across, "Bad Santa" star who played a serial killer on FX's "Fargo": 2 wds. |
| 59% | PATRICKSTEWART | 14 | Actor who played Captain Jean-Luc Picard on "Star Trek: The Next Generation": 2 wds. |
| 58% | DEBBIEALLEN | 11 | "Grey's Anatomy" star who played a dance teacher on "Fame" (2 wds.) |
| 58% | MRT | 3 | Actor who played B.A. Baracus on "The A-Team": 2 wds. |
| 58% | ALANCUMMING | 11 | "The Good Wife" star who played a closeted mayor on "Schmigadoon!" and a vengeful butcher on "Schmicago": 2 wds. |
| 58% | JACKQUAID | 9 | "Star Trek: Lower Decks" actor who plays newbie vigilante Hughie Campbell on "The Boys": 2 wds. |
| 57% | PETERFALK | 9 | Actor who played a homicide detective in Los Angeles on "Columbo" (2 wds.) |
| 57% | MARKHARMON | 10 | A former college football star who plays Leroy Gibbs on "NCIS": 2 wds |
| 57% | MRT | 3 | Actor who played B.A. on "The A-Team": 2 wds. |
| 57% | JOHNAMOS | 8 | Actor who starred on "Good Times," a Norman Lear sitcom: 2 wds. |
| 57% | SHERMANHEMSLEY | 14 | Actor who starred on "The Jeffersons," a Norman Lear sitcom: 2 wds. |
| 57% | DAVIDCASSIDY | 12 | Actor who played a singing sibling on "The Partridge Family" (2 wds.) |
| 56% | CONNIEBRITTON | 13 | "Nashville" star who played a guidance counselor on "Friday Night Lights" (2 wds.) |
| 56% | GLENNHOWERTON | 13 | "It's Always Sunny ..." actor who plays a biology teacher on NBC's "A.P. Bio": 2 wds. |
| 56% | CARROLLOCONNOR | 14 | Actor who starred on "All in the Family," a Norman Lear sitcom: 2 wds. |
| 56% | PETERFALK | 9 | Jewish actor who played Italian American Lieutenant Columbo on "Columbo": 2 wds. |
| 56% | WILWHEATON | 10 | "Star Trek: The Next Generation" actor who voices amnesiac chef Earl Harlan, a character on 15-/51-Across: 2 wds. |
| 56% | MRT | 3 | Tough actor who starred on "The A-Team": 2 wds. |
| 56% | WOODYHARRELSON | 14 | "Solo: A Star Wars Story" actor who plays Tallahassee in "Zombieland: Double Tap": 2 wds. |
| 56% | DANNYMCBRIDE | 12 | "Vice Principals" actor who played a former pro baseball player on "Eastbound & Down": 2 wds. |
| 56% | TEDDANSON | 9 | "The Good Place" actor who played a former pro baseball player on "Cheers": 2 wds. |
| 56% | JEFFGOLDBLUM | 12 | Actor famous for "Jurassic Park" who appeared as a guest star on "Friends": 2 wds. |
| 55% | DOVECAMERON | 11 | "Liv and Maddie" star who played a farmer's daughter on "Schmigadoon!" and a cabaret performer on "Schmicago": 2 wds. |