| 100% | BORG | 4 | "Star Trek: First Contact" villains, with "the" |
| 76% | NEMESIS | 7 | Star Trek: __, film with Tom Hardy as the villain |
| 58% | XXXX | 4 | Recurring "Star Trek" villains, with "the" |
| 56% | BORG | 4 | "Star Trek: First Contact" baddies |
| 54% | REAGAN | 6 | First U.S. president with a star on the Hollywood Walk of Fame |
| 54% | ANAGRAM | 7 | The first half of each starred clue, with respect to its second half |
| 54% | KEKEPALMER | 10 | "Turnt Up With the Taylors" star whose first name has a repeated "ee" sound: 2 wds. |
| 53% | DAVIDCUFIELD | 12 | First living magician with a star on the Hollywood Walk of Fame |
| 52% | MET | 3 | Shook hands with (a hint to the first words of the starred clues) |
| 52% | NERO | 4 | Villain in the 2009 "Star Trek" film |
| 52% | RIDDLER | 7 | Villain with the "real" name Edward Nigma |
| 51% | BORG | 4 | "Star Trek" villains with a hive mind |
| 50% | MEASURETWICE | 12 | With 66-Across, carpentry adage that also describes the first words of the answers to the starred clues |
| 50% | RIKER | 5 | "Star Trek: The Next Generation" first officer played by Jonathan Frakes |
| 49% | NERO | 4 | Villain in the "Star Trek" reboot played by Eric Bana |
| 49% | JEANLUC | 7 | First name on "Star Trek: The Next Generation" |
| 49% | KLINGON | 7 | Star Trek species with ribbed foreheads |
| 49% | WRATH | 5 | Star Trek II: The ___ of Kahn |
| 49% | INITIAL | 7 | With 36-Across, first encounter, or what the answers to the starred clues make? |
| 49% | UPN | 3 | Bygone channel that launched with the two-hour pilot of "Star Trek: Voyager" |
| 49% | ASTRO | 5 | Concerned with the stars |
| 49% | ATOMIC | 6 | With 38-Down, property of the first part of the answer to each starred clue (appropriately positioned in the grid) |
| 48% | COMINGINHOT | 11 | Arriving with great speed, and what the first words of the answers to the starred clues are doing? |
| 48% | SYLLABLES | 9 | What the first word of the answer to each starred clue counts, with respect to the second word |
| 48% | SPOCK | 5 | Star Trek character with human-Vulcan heritage |
| 48% | VULCAN | 6 | Star Trek alien species with pointed ears |
| 48% | EVE | 3 | Level with the first woman |
| 48% | LEO | 3 | Constellation with the star Regulus |
| 48% | ORION | 5 | Constellation with the star Betelgeuse |
| 48% | ORION | 5 | Constellation with the star Rigel |