| 100% | LEAST | 5 | "That's the ___ of my problems" |
| 75% | BANE | 4 | “Ugh, that’s the ___ of my existence” |
| 74% | LEAST | 5 | "That's the ___ of my worries!" |
| 74% | LEAST | 5 | "That's the ___ of my concerns!" |
| 74% | LEAST | 5 | "That's the ___ of my worries" |
| 68% | NONE | 4 | "But that's ___ of my business," quote from the popular Kermit drinking tea meme |
| 67% | ANXIETY | 7 | Feelings of fear that cause problems in the body |
| 66% | DAYS | 4 | "... those were the best ___ of my life..." |
| 65% | AHA | 3 | "So THAT's the problem!" |
| 65% | JOB | 3 | Book that originated the phrase "skin of my teeth" |
| 63% | ENDO | 4 | Prefix that’s the opposite of 38-Down |
| 63% | COAL | 4 | Kind of mine for The Police's canary |
| 63% | DYS | 3 | Prefix that's the opposite of eu- |
| 63% | ANTI | 4 | Prefix that's the opposite of "pro-" |
| 63% | CACAO | 5 | Tree that's the source of chocolate |
| 63% | NUTMEG | 6 | Tree that's the source of mace |
| 63% | POPPY | 5 | Flower that's the source of opium |
| 63% | ENE | 3 | Direction that's the reverse of WSW |
| 63% | HEART | 5 | Organ that's the symbol of love |
| 63% | MINI | 4 | Prefix that's the opposite of "maxi-" |
| 63% | CLAM | 4 | Animal that's the epitome of happiness |
| 63% | CACAO | 5 | Bean that's the source of chocolate |
| 63% | POST | 4 | Prefix that's the opposite of "pre-" |
| 63% | MAXI | 4 | Prefix that's the opposite of "mini-" |
| 63% | ANTI | 4 | Prefix that's the opposite of 28a |
| 63% | PRE | 3 | Prefix that's the opposite of "post" |
| 63% | JOURNEYMAN | 10 | Language that's the source of "gesundheit" |
| 63% | PRE | 3 | Prefix that's the opposite of "post-" |
| 63% | AGAVE | 5 | Plant that's the source of mescal |
| 63% | YEW | 3 | Tree that's the source of Taxol |