| 100% | ODD | 3 | "The ___ Couple" (2015-2017 CBS sitcom) |
| 84% | ODD | 3 | "The ___ Couple" (1970-1975 and 2015-2017 sitcom) |
| 83% | ODD | 3 | "The ___ Couple" (2015-2017 sitcom) |
| 68% | ODD | 3 | "The ___ Couple" (CBS sitcom) |
| 66% | ODD | 3 | "The ___ Couple" (2015 remake of a classic sitcom) |
| 60% | BIG | 3 | CBS sitcom "The ___ Bang Theory" |
| 58% | BANG | 4 | "The Big ___ Theory" (former CBS sitcom) |
| 58% | LIFEIN | 6 | With 32-Across, CBS sitcom with the tagline "Family. Some assembly required": 2 wds. |
| 58% | ODD | 3 | "The ___ Couple" (classic sitcom) |
| 58% | DYKE | 4 | "The Dick Van ___ Show," CBS sitcom which was immensely popular in the '60s |
| 57% | DRE | 3 | ___ and Rainbow Johnson, fictional couple from the sitcom "Black-ish" |
| 57% | MURPHYBROWN | 11 | 1988-1998 CBS sitcom on which 28-Across played the title news anchor: 2 wds. |
| 56% | ANDY | 4 | "The ___ Griffith Show," CBS sitcom which was immensely popular in the '60s |
| 56% | BIGBANGTHEORY | 13 | CBS sitcom about geeky roommates, with "The": 3 wds. |
| 55% | ODD | 3 | "The ___ Couple" (1970s Tony Randall sitcom) |
| 55% | ODD | 3 | "The ___ Couple" (Matthew Perry's sitcom) |
| 55% | ODD | 3 | "The ___ Couple," sitcom starring Matthew Perry |
| 54% | ODD | 3 | "The ___ Couple" (Tony Randall/Jack Klugman sitcom) |
| 54% | ODD | 3 | "The ___ Couple" (Matthew Perry/Thomas Lennon sitcom) |
| 54% | ODD | 3 | "The ___ Couple" (old sitcom about mismatched roommates) |
| 54% | ODD | 3 | "The ___ Couple" (1970s sitcom about mismatched roommates) |
| 54% | LIFEINPIECES | 12 | 2015-2019 CBS sitcom in which Dianne Wiest played Dr. Joan Short: 3 wds. |
| 54% | BOAT | 4 | "Fresh Off the ___" (2015-2020 sitcom) |
| 53% | MOM | 3 | CBS sitcom |
| 53% | MARK | 4 | ___ Cendrowski, director of CBS sitcom "The Big Bang Theory" |
| 53% | ANNA | 4 | Actress Faris of the CBS sitcom "Mom" |
| 52% | THEUNICORN | 10 | CBS sitcom starring 18-Across and 33-Across about a recently widowed father who re-enters the dating scene (2 wds.) |
| 51% | STEVEKERR | 9 | NBA coach for the Warriors who won the championship in 2015 and 2017: 2 wds. |
| 51% | ARNIE | 5 | 1970-72 CBS sitcom |
| 51% | SYLVIAFOWLES | 12 | Minnesota Lynx center who was the WNBA Finals MVP in 2015 and 2017 (2 wds.) |