| 100% | ENOLA | 5 | "The ___ Holmes Mysteries," young adult series about a 14-year-old detective |
| 56% | ENOLA | 5 | "The ___ Holmes Mysteries" (young adult detective series) |
| 55% | ENOLA | 5 | "The ___ Holmes Mysteries," young adult series made into a 2020 film |
| 49% | ENOLA | 5 | Holmes in a young adult mystery series |
| 49% | ENOLA | 5 | "The ___ Holmes Mysteries" (young adult series) |
| 43% | TOOOLD | 6 | Like a 14-year-old vis-à-vis the Little League World Series |
| 39% | TIGEREYES | 9 | Young adult novel by 38-Across about a girl coping with the death of her father (2 wds.) |
| 39% | ENOLA | 5 | "The __ Holmes Mysteries," series about Sherlock's teenage sister |
| 37% | THESEARCHER | 11 | 2020 novel by Tana French about a retired detective who begins investigating an old mystery in rural Ireland (2 wds.) |
| 37% | MONK | 4 | TV series about a detective with OCD |
| 37% | NANCYDREW | 9 | Long-running book series about a girl detective |
| 37% | MONK | 4 | Tony Shalhoub series about a detective with OCD |
| 36% | TOD | 3 | "The Chronicles of Vladimir ___" (hit young adult book series about a vampire) |
| 36% | NARUTO | 6 | Popular manga and anime series about a young ninja |
| 36% | SHERLOCK | 8 | PBS "Masterpiece" series about a detective played by Benedict Cumberbatch |
| 36% | PSYCH | 5 | TV series about a detective who pretended to have ESP |
| 36% | PSYCH | 5 | USA Network series about a detective pretending to have ESP |
| 35% | PSYCH | 5 | Former TV series about a detective who pretended to have ESP |
| 35% | HANNA | 5 | Film and TV series about a girl raised in the wilderness |
| 35% | SCOOBYDOO | 9 | Animated series about mystery-solving with a dog |
| 34% | BAYWATCH | 8 | TV series about the routine of a lifeguard team |
| 34% | THEOFFICE | 9 | TV series about the routine of a paper company |
| 34% | LADIES | 6 | "The No. 1 ___ Detective Agency" (first novel in a mystery series by Alexander McCall Smith) |
| 33% | WORLD | 5 | "Out of This ___," 1987 TV series about a supernatural teenager which inspired the show "WandaVision" |
| 33% | LASTSONG | 8 | Novel by Nicholas Sparks about a 17 year old teen who is sent to stay with her father in the summer, "The ___": 2 wds. |
| 33% | TYSON | 5 | "Mike ___ Mysteries" (Adult Swim series about a famous boxer) |
| 33% | BERTHACOOL | 10 | Detective in a series of Erle Stanley Gardner mysteries |
| 33% | KIPOANDTHEAGE | 13 | With 32-Across, animated series about a girl from beneath the Earth's surface: 4 wds. |
| 32% | EARP | 4 | “Wynonna ___” (sci-fi series about the great-great-granddaughter of a legendary lawman) |
| 32% | EARP | 4 | Wynonna ___ (long-running Canadian television series about the descendant of a famous lawman) |