| 100% | VICAR | 5 | "The ___ of Christ", bestselling 1979 novel about the life of Declan Walsh |
| 47% | OURMISSINGHARTS | 15 | Celeste Ng novel about the absence of male deer in people's lives? |
| 45% | ULYSSES | 7 | Novel about one day in the life of three Dubliners |
| 44% | SONGOFSOLOMON | 13 | 1977 novel by Toni Morrison which is about the life of an African-American man living in Michigan: 3 wds. |
| 43% | THE | 3 | "All in ___ Family," CBS sitcom about the life of a working-class father and his family that ran from 1971 - 1979 |
| 42% | SHOWMAN | 7 | The Greatest __; film about the life of PT Barnum |
| 42% | APASSAGETOINDIA | 15 | Novel about the trial of Dr. Aziz |
| 42% | MIND | 4 | “The Life of the ___,” Christine Smallwood novel about lost opportunities to become a mother and professor (March, 2021) |
| 41% | NORTHLAND | 9 | Canadian 1942 documentary about the life of miners |
| 41% | BEYONDTHE | 9 | 2004 biopic about the life of Bobby Darin |
| 40% | MOHICANS | 8 | Fenimore Cooper novel about the last of this tribe |
| 40% | LADY | 4 | ___ Whistledown, author who gossips about the life of the Bridgertons |
| 39% | INTO | 4 | Sean Penn's "___ the Wild," about the life of Chris McCandless |
| 39% | SOA | 3 | Crime tragedy TV series about the life of Jax Teller: Abbr. |
| 39% | ABBEY | 5 | "Northanger ___" (Jane Austen novel about the daughter of a rural clergyman) |
| 39% | ACTS | 4 | "Death Defying ___," film about the life of Hungarian-American escapologist Harry Houdini |
| 39% | MRSDALLOWAY | 11 | Virginia Woolf's novel about a day in the life of a woman in England post World War I: 2 wds. |
| 39% | NORMARAE | 8 | 1979 film based on the life of Crystal Lee Sutton |
| 38% | TIGERKING | 9 | Smash-hit Netflix show about the life of the former zookeeper Joe Exotic |
| 38% | TARBABY | 7 | 1981 novel about the interplay of privilege and poverty in a Caribbean romance |
| 38% | BELIEFS | 7 | Convictions a person has about the meaning of life |
| 38% | TABLE | 5 | "Chef's ___," Netflix show about the lives of the world's most successful chefs |
| 38% | UNREAL | 6 | Drama TV series about the life of a dating show producer starring Shiri Appleby |
| 38% | BELOVED | 7 | 1987 Pulitzer-winning novel about the haunting of a formerly enslaved family's home |
| 37% | SATYAGRAHA | 10 | 1979 opera by Philip Glass loosely based on the life of Mahatma Gandhi |
| 37% | THEPILOTSWIFE | 13 | Novel by 29-Across about the aftermath of a plane crash (3 wds.) |
| 37% | PUPFICTION | 10 | Movie about the early life of Lassie? |
| 37% | CLARKE | 6 | Marcus —, author of 1874 novel For the Term of his Natural Life |
| 37% | ELEVEN | 6 | "___ Minutes," 2003 novel by Paulo Coelho that follows the life of Maria |