| 100% | FINAL | 5 | "The ___ Problem," Sherlock Holmes story that was originally intended by Arthur Conan Doyle to be his last Holmes-related work |
| 43% | FINAL | 5 | "The ___ Problem," Sherlock Holmes short story by Arthur Conan Doyle |
| 41% | POLE | 4 | "The Captain of the ___-Star," short story by Arthur Conan Doyle that was published in the Temple Bar |
| 39% | BAND | 4 | "The Adventure of the Speckled ___," Sherlock Holmes short story by Arthur Conan Doyle |
| 38% | FINAL | 5 | & 16A The —, Sherlock Holmes story by Arthur Conan Doyle first published in the Strand Magazine in December 1893 |
| 37% | SIGNOFFOUR | 10 | The —, 1890 novel by Arthur Conan Doyle featuring Sherlock Holmes |
| 36% | PIPS | 4 | "The Five Orange ___," Sherlock Holmes short story by Arthur Conan Doyle |
| 36% | SILVERBLAZE | 11 | 1892 story by Arthur Conan Doyle featuring detective Sherlock Holmes |
| 35% | LOT | 3 | "___ No. 249," gothic horror short story by Arthur Conan Doyle that influenced the Mummy horror genre |
| 34% | FOUR | 4 | "The Sign of the ___," Sherlock Holmes novel by Arthur Conan Doyle |
| 34% | BASKERVILLES | 12 | "The Hound of the ___," Sherlock Holmes novel by Arthur Conan Doyle |
| 34% | SCANDAL | 7 | "A ___ in Bohemia," Sherlock Holmes short story by Arthur Conan Doyle |
| 34% | STONE | 5 | "Rodney ___," gothic mystery novel by Arthur Conan Doyle that was adapted as "The House of Temperley" |
| 33% | LESTRADE | 8 | Fictional Scotland Yard inspector in stories by Arthur Conan Doyle involving Sherlock Holmes who first appeared in A Study in Scarlet |
| 33% | MORIARTY | 8 | Professor James —, arch-enemy of Sherlock Holmes in stories by Arthur Conan Doyle |
| 33% | BLUE | 4 | "The Adventure of the ___ Carbuncle," Sherlock Holmes story that is set around Christmas |
| 32% | BAKERSTREET | 11 | & 1A Group of street urchins who aid Sherlock Holmes in various stories by Arthur Conan Doyle |
| 31% | VALLEY | 6 | "The Mystery of the Sasassa ___," first published work by Arthur Conan Doyle |
| 31% | IRENEADLER | 10 | Fictional opera singer/actress who outsmarts Sherlock Holmes in the Arthur Conan Doyle story "A Scandal in Bohemia" (2 wds.) |
| 31% | PASTICHE | 8 | Sherlock Holmes story not by Conan Doyle, e.g. |
| 31% | SIR | 3 | ___ Arthur Conan Doyle (title for the creator of Sherlock Holmes) |
| 30% | IRENEADLER | 10 | Holmes character created by Arthur Conan Doyle who may be modeled after Lillie Langtry or Lola Montez |
| 30% | IRENE | 5 | ___ Adler, iconic character from the Sherlock Holmes stories who was played by Lara Pulver on screen |
| 30% | MARY | 4 | ___ Morstan, Watson's wife in the Sherlock Holmes stories who was played by Amanda Abbington on screen |
| 29% | HOLMES | 6 | Sherlock ___, Sir Arthur Conan Doyle's brilliant detective who is never seen without his signature deerstalker hat |
| 29% | BELL | 4 | Joseph ___, surgeon whom Arthur Conan Doyle cites as inspiration for the character of Sherlock Holmes |
| 29% | STUDY | 5 | "A ___ in Scarlet" (first Sherlock Holmes novel by Arthur Conan Doyle) |
| 29% | MORIARTY | 8 | Professor James —, archenemy of Sherlock Holmes in tales by Arthur Conan Doyle |
| 28% | STING | 5 | Elven short-sword that was discovered by Bilbo Baggins and later gifted to his heir, Frodo Baggins |
| 28% | LANDOFMIST | 10 | The —, 1926 novel by Arthur Conan Doyle |