| 100% | LOST | 4 | "The ___ Symbol," 2009 thriller novel by Dan Brown set in Washington D.C. |
| 75% | THELOSTSYMBOL | 13 | Thriller written by Dan Brown set in Washington D.C. after the events of "The Da Vinci Code": 3 wds. |
| 54% | ORIGIN | 6 | 2017 mystery thriller novel by Dan Brown that has been set in Spain |
| 48% | INFERNO | 7 | Mystery thriller novel written by Dan Brown set in Florence which is inspired by Dante's work |
| 44% | LOSTSYMBOL | 10 | The —, 2009 novel by Dan Brown |
| 41% | RAMA | 4 | "Rendezvous with ___," 1973 novel by Arthur C. Clarke that is set in the 2130s |
| 38% | INFERNO | 7 | 2013 novel by Dan Brown, with prominent references to the medieval poet Dante |
| 38% | ANGELS | 6 | "___ and Demons," 2000 novel by Dan Brown that introduces the character Robert Langdon |
| 38% | NARNIA | 6 | Setting of seven fantasy novels by C S Lewis published in the 1950s |
| 37% | COLUMBIA | 8 | The C in Washington, D.C. |
| 37% | HAMMER | 6 | "The ___ of God," 1993 sci-fi novel by Arthur C. Clarke that is set in the year 2109 |
| 37% | COLUMBIA | 8 | The C in Washington, D.C., previously |
| 37% | EST | 3 | Clock setting in Washington, D.C. (Abbr.) |
| 37% | EDT | 3 | Summer setting in Washington, D.C.: Abbr. |
| 36% | EDT | 3 | Summer clock setting in Washington, D.C. (Abbr.) |
| 36% | SONGS | 5 | "The ___ of Distant Earth," 1986 sci-fi novel by Arthur C. Clarke that is set in the early 3800s |
| 36% | MANOFWAR | 8 | 2003 novel by Alexander Kent set in the West Indies |
| 35% | CANON | 5 | "The 7th ___," 2016 legal thriller novel by Robert Dugoni set in San Francisco |
| 35% | JAZZ | 4 | Historical novel by Toni Morrison set in Harlem in the 1920s |
| 35% | FAIREST | 7 | 2006 novel by Gail Carson Levin set in the kingdom of Ayortha |
| 35% | ONEBYONE | 8 | Mystery novel by 45-Across set in the French Alps (3 wds.) |
| 35% | THEFOURWINDS | 12 | Novel by 29-Across set in the Great Plains during the Dust Bowl era (3 wds.) |
| 35% | THEADDRESS | 10 | Novel by 39-Across set in New York City's apartment building The Dakota (2 wds.) |
| 34% | COLUMBIA | 8 | What the C in Washington, D.C. stands for |
| 34% | INFERNO | 7 | 2013 novel by Dan Brown |
| 34% | THEGREATALONE | 13 | 2018 novel by 44-Across set in Alaska after the Vietnam War (3 wds.) |
| 34% | DIGITAL | 7 | & 13D 1998 novel by Dan Brown |
| 34% | DECEPTION | 9 | & 9D 2001 novel by Dan Brown |