| 100% | HANDMAIDS | 9 | "The ___ Tale", Hulu's dystopian drama web television, based on a novel of the same name by Margaret Atwood |
| 60% | BRUCEMILLER | 11 | Creator of the Hulu TV series "The Handmaid's Tale," based on the 1985 novel of the same name by Margaret Atwood: 2 wds. |
| 57% | FOUNTAINHEAD | 12 | "The ___," 1949 drama film starring Gary Cooper which was based on a novel of the same name by Ayn Rand |
| 57% | SWEETBITTER | 11 | American drama TV series starring Ella Purnell which is based on a novel of the same name by Stephanie Danler |
| 56% | THEALIENIST | 11 | American period drama TV series starring Dakota Fanning which is based on a novel of the same name by Caleb Carr: 2 wds. |
| 56% | ALTEREDCARBON | 13 | American dystopian sci-fi TV series starring Joel Kinnaman which is based on a novel of the same name by Richard K. Morgan: 2 wds. |
| 51% | MAY | 3 | "What Dreams ___ Come," fantasy drama film based on a novel of the same name starring Robin Williams |
| 51% | TENTHOUSAND | 11 | "___ Saints," 2015 Ethan Hawke starrer drama film based on the novel of the same name by Eleanor Henderson: 2 wds. |
| 50% | RIPLEYSGAME | 11 | 2002 thriller drama starring Lena Headey, which is based on the novel of the same name by Patricia Highsmith: 2 wds. |
| 49% | THESEAOFGRASS | 13 | 1947 Western drama film directed by Elia Kazan based on a 1936 novel of the same name, starring Katharine Hepburn: 4 wds. |
| 47% | OUTSIDERS | 9 | "The ___," 1983 film starring Diane Lane based on a novel of the same name |
| 46% | NOW | 3 | "The Spectacular ___," romantic comedy film which was based on a book of the same name by Tim Tharp |
| 46% | ELOI | 4 | The oppressed race from the 2002 film "The Time Machine," based on the novel of the same name by H.G Wells |
| 46% | MONEYBALL | 9 | Brad Pitt's 2011 sports drama film based on a Michael Lewis novel of the same name in which 20a plays his ex-wife |
| 45% | PSYCHO | 6 | 1960 American thriller film directed by Alfred Hitchcock based on a 1959 novel of the same name |
| 45% | THENIGHTAGENT | 13 | Netflix action thriller series starring 18-Across and Luciane Buchanan based on the novel of the same name by 40-Across (3 wds.) |
| 45% | INTOTHEWILD | 11 | 2007 film starring Emile Hirsch based on a book of the same name by Jon Krakauer set in the Alaskan wilderness: 3 wds. |
| 44% | FIVE | 4 | "___ on a Treasure Island," 1957 British film serial based on the novel of the same name by Enid Blyton |
| 43% | WATCHMEN | 8 | American satirical and dystopian superhero film directed by Zack Snyder which is based on a DC Comics limited series of the same name |
| 43% | TEEN | 4 | "___ Wolf," supernatural drama TV series based on the 1985 film of the same name, about a youngster who is bitten by a werewolf |
| 43% | BLACK | 5 | "The ___ Stallion," 1979 adventure film based on a 1941 children's novel of the same name |
| 43% | FORRESTGUMP | 11 | Tom Hanks' 1994 drama film based on a Winston Groom novel of the same name in which 20a plays his love interest: 2 wds. |
| 43% | SOPHIESCHOICE | 13 | American drama film of 1982 starring Meryl Streep which is an adaptation of a novel of the same name by William Styron: 2 wds. |
| 42% | ROOTS | 5 | American historical drama miniseries based on Alex Haley's novel of the same name |
| 42% | ALADDIN | 7 | 1992 film based on a folktale of the same name |
| 42% | TRON | 4 | Arcade game based on a film of the same name |
| 42% | RICH | 4 | Jon M. Chu's 2018 film "Crazy ___ Asians" which is based on a 2013 novel of the same name |
| 42% | AMERICANGODS | 12 | Starz fantasy drama based on 16-Across's 2001 novel of the same name: 2 wds. |
| 41% | CHICKENLITTLE | 13 | 2005 film based on a folktale of the same name: 2 wds. |
| 41% | SHINING | 7 | "The ___," 1980 horror film starring Jack Nicholson based on the novel of the same name |