| 100% | ROBERTDOWNEYJR | 14 | "The Avengers" actor who played the title role in "Chaplin": 3 wds., abbr. |
| 68% | JAREDLETO | 9 | "Blade Runner 2049" actor who plays the title role in "Morbius" (2 wds.) |
| 68% | LIAMNEESON | 10 | "Schindler's List" actor who plays the title role in "Marlowe" (2 wds.) |
| 68% | MATTHEWRHYS | 11 | "The Americans" actor who plays the title role in HBO's "Perry Mason": 2 wds. |
| 67% | DENNISQUAID | 11 | "Flight of the Phoenix" actor who plays the title role in 16-Across: 2 wds. |
| 67% | MICHAELKEATON | 13 | "Mr. Mom" actor who played the title role in 40-Across (2 wds.) |
| 67% | TONYTODD | 8 | "Final Destination" actor who plays the title role in 16-Across: 2 wds. |
| 67% | DWAYNEJOHNSON | 13 | "Hobbs & Shaw" actor who plays the title role in "Black Adam" (2 wds.) |
| 67% | AUSTINBUTLER | 12 | "Once Upon a Time in Hollywood" actor who plays the title role in "Elvis" (2 wds.) |
| 67% | HENRYFONDA | 10 | "On Golden Pond" actor who played the title role in 32-Across: 2 wds. |
| 67% | HARRISONFORD | 12 | "The Fugitive" actor who plays the title role in "Indiana Jones and the Dial of Destiny" (2 wds.) |
| 67% | KEANUREEVES | 11 | "The Matrix Resurrections" actor who plays the title role in "John Wick: Chapter 4" (2 wds.) |
| 67% | TARONEGERTON | 12 | "Rocketman" actor who plays the title role in the 2018 film "Robin Hood" (2 wds.) |
| 67% | RUSSELLCROWE | 12 | "Gladiator" actor who plays the title role in the 2010 film "Robin Hood" (2 wds.) |
| 66% | EWANMCGREGOR | 12 | "Beauty and the Beast" actor who plays the title role in the new movie "Christopher Robin": 2 wds. |
| 66% | EDDIEMURPHY | 11 | "Coming to America" actor who played the title role in 1998's "Dr. Dolittle": 2 wds. |
| 66% | ROBERTDENIRO | 12 | "Joy" actor who plays the title character in 18-Across: 3 wds. |
| 66% | DEREKJACOBI | 11 | "The King's Speech" actor who plays the title role in the film "Cyrano de Bergerac" (2 wds.) |
| 66% | EVANS | 5 | Chris —, US actor who played the title role in 2011 action film Captain America: The First Avenger |
| 65% | PETERDINKLAGE | 13 | "Game of Thrones" actor who plays the title character in "The Toxic Avenger": 2 wds. |
| 63% | NATE | 4 | Actor who plays the title role in "Castle" |
| 62% | CRAIGTNELSON | 12 | "Parenthood" actor who plays the title role on 60-Across (3 wds.) |
| 62% | TONYSHALHOUB | 12 | Actor who played the title role in US television series Monk |
| 62% | KARLURBAN | 9 | Actor who played the title role in 2012 action film Dredd |
| 62% | RON | 3 | Actor who played the title role in 2004 action film Hellboy |
| 61% | REDSKELTON | 10 | Actor who played the title role in 1953 film drama The Clown |
| 61% | LARRYPARKS | 10 | Actor who played the title role in 1946 biopic The Jolson Story |
| 61% | SEAN | 4 | Actor who played the title role in 2007 film thriller The Hitcher |