| 100% | MAYIM | 5 | "The Big Bang Theory" actress __ Bialik who is also a scheduled 2021 "Jeopardy!" guest host |
| 48% | KALEYCUOCO | 10 | "The Big Bang Theory" actress who says "Every trip is a big deal" in Priceline.com commercials (2 wds.) |
| 47% | MAYIM | 5 | The Big Bang Theory actress Bialik |
| 43% | MAYIMBIALIK | 11 | "The Big Bang Theory" actress who earned a doctorate in neuroscience from 33-Down: 2 wds. |
| 41% | BILLIEEILISH | 12 | "Bad Guy" singer who was both the host and musical guest on a 2021 "Saturday Night Live" episode: 2 wds. |
| 41% | CHUCKLORRE | 10 | Creator of "Two and a Half Men" and "The Big Bang Theory," who is also the co-creator of CBS's new show "Young Sheldon": 2 wds. |
| 39% | RAJ | 3 | Only "The Big Bang Theory" friend who is unmarried when the series ends |
| 39% | KALEYCUOCO | 10 | "The Big Bang Theory" actress who voices Harley Quinn |
| 37% | RAJ | 3 | "The Big Bang Theory" character who was born in New Delhi |
| 36% | LAMARR | 6 | Actress Hedy who was also a mathematician and inventor |
| 36% | YARASHAHIDI | 11 | "The Sun Is Also a Star" actress who plays Zoey on the Freeform sitcom "Grown-ish": 2 wds. |
| 36% | MAYIM | 5 | Actress Bialik of "The Big Bang Theory" |
| 36% | JIMPARSONS | 10 | "The Big Bang Theory" actor who was nominated for an Emmy Award for "Hollywood" (2 wds.) |
| 36% | AMY | 3 | ___ Farrah Fowler, neuroscientist from "The Big Bang Theory" who has a Ph.D. in Neurobiology |
| 35% | MAYIM | 5 | ___ Bialik, Emmy-nominated actress best known for her role in "The Big Bang Theory" who has a degree in Neuroscience |
| 35% | ARIANAGRANDE | 12 | "7 Rings" singer who was both the host and musical guest on a 2016 "SNL" episode: 2 wds. |
| 35% | MAYIM | 5 | Actress __ Bialik of "The Big Bang Theory" |
| 35% | MAYIM | 5 | Actress ___ Bialik of "The Big Bang Theory" |
| 35% | ADAMWEST | 8 | Batman actor from the 1960s who did a guest appearance on "The Big Bang Theory": 2 wds. |
| 34% | MAYIM | 5 | ___ Bialik, actress who plays Amy Farrah Fowler in "The Big Bang Theory" |
| 34% | AUDRAMCDONALD | 13 | Six-time Tony-winning actress who was a guest on the "On Broadway" episode of "Finding Your Roots" in 2021 (2 wds.) |
| 34% | MANDYPATINKIN | 13 | Tony- and Emmy-winning actor who was a guest on the "On Broadway" episode of "Finding Your Roots" in 2021 (2 wds.) |
| 34% | MAYIM | 5 | ___ Bialik, actress of "The Big Bang Theory" |
| 34% | NICKJONAS | 9 | "Jealous" pop singer who both hosted and was the musical act in a 2021 "SNL" episode: 2 wds. |
| 34% | MELISSA | 7 | 'The Big Bang Theory' actress Rauch |
| 34% | SARA | 4 | "The Big Bang Theory" actress Gilbert |
| 34% | CUOCO | 5 | "The Big Bang Theory" actress Kaley |
| 34% | MAYIMBIALIK | 11 | Former "Blossom" and "The Big Bang Theory" star who co-hosts "Jeopardy!" (2 wds,) |
| 33% | RAJ | 3 | ___ Koothrappali, astrophysicist from "The Big Bang Theory" who forms a band with his friend and writes songs about sci-fi characters |
| 33% | TNT | 3 | Channel that doesn't air The Big Bang Theory, even though that would be apt |