| 100% | AMY | 3 | "The Big Bang Theory" chum of Bernadette and Penny |
| 75% | RAJ | 3 | "The Big Bang Theory" chum of Sheldon and Leonard |
| 72% | AMY | 3 | Friend of Penny and Bernadette on "The Big Bang Theory" |
| 63% | SYNDROME | 8 | "The Stockholm ___," episode of "The Big Bang Theory" where Bernadette and Howard leave their kids for the first time |
| 61% | RAJ | 3 | "The Big Bang Theory" pal of Sheldon, Leonard, and Howard |
| 61% | TAKEI | 5 | "Star Trek" actor George who has had cameos on "The Big Bang Theory" and "King of the Nerds" |
| 60% | NEBRASKAN | 9 | State identity of Penny from The Big Bang Theory |
| 59% | BIALIK | 6 | The Big Bang Theory and Blossom star Mayim |
| 57% | FACTORY | 7 | Big Bang Theory Penny worked at the Cheesecake __ |
| 55% | RAJ | 3 | Koothrappali of The Big Bang Theory |
| 54% | ACTRESS | 7 | What Penny of "The Big Bang Theory" aspires to be, professionally |
| 53% | YOUNGSHELDON | 12 | "The Big Bang Theory" prequel about one of the scientists as a boy (2 wds.) |
| 51% | LEMAITRE | 8 | Georges __, physicist of the Big Bang theory |
| 51% | RAJ | 3 | Pal of Sheldon and Leonard on "The Big Bang Theory" |
| 51% | LORRE | 5 | "The Big Bang Theory" and "Young Sheldon" co-creator Chuck |
| 51% | LORRE | 5 | Chuck who created "The Big Bang Theory" and "Mom" |
| 51% | LEONARD | 7 | "The Big Bang Theory" friend who married Penny |
| 50% | BAZINGA | 7 | The Big Bang Theory catchword |
| 50% | NERD | 4 | The Big Bang Theory stereotype |
| 50% | LORRE | 5 | Chuck ___, cocreator of "The Big Bang Theory" and "Two and a Half Men" |
| 50% | JIMPARSONS | 10 | Actor who portrayed Sheldon Cooper in "The Big Bang Theory," and is the narrator in "Young Sheldon": 2 wds. |
| 50% | MAYIM | 5 | The Big Bang Theory actress Bialik |
| 49% | SHELDON | 7 | The Big Bang Theory spin-off, Young __ |
| 49% | YOUNGSHELDON | 12 | "The Big Bang Theory" prequel starring 13-Across and 27-Across (2 wds.) |
| 49% | YLEM | 4 | Matter in the Big Bang theory |
| 48% | CHANGE | 6 | "The ___ Constant," episode of "The Big Bang Theory" where Sheldon and Amy wait to hear if they've won the Nobel Prize |
| 48% | JIM | 3 | Parsons of "The Big Bang Theory" |
| 48% | CUOCO | 5 | Kaley of "The Big Bang Theory" |
| 48% | KALEY | 5 | Cuoco of "The Big Bang Theory" |
| 48% | PARSONS | 7 | Jim of "The Big Bang Theory" |