| 100% | JOHNGOODMAN | 11 | "The Conners" actor who played Big Dan in "O Brother, Where Art Thou?": 2 wds. |
| 67% | GEORGECLOONEY | 13 | "Ocean's Eleven" actor who played Everett in "O Brother, Where Art Thou?": 2 wds. |
| 60% | HOLLYHUNTER | 11 | "The Piano" actress who played Penny in "O Brother, Where Art Thou?": 2 wds. |
| 52% | MICHAELDOUGLAS | 14 | Actor who played Dan Gallagher, the husband, in "Fatal Attraction": 2 wds. |
| 51% | GARYSINISE | 10 | "CSI: NY" actor who plays guitar in the Lt. Dan Band: 2 wds. |
| 50% | PATMORITA | 9 | Actor who plays Mr. Miyagi in the 1984 martial arts drama film "The Karate Kid": 2 wds. |
| 49% | GARYBURGHOFF | 12 | Actor who played "Radar" O'Reilly in both the movie and TV series "M*A*S*H": 2 wds. |
| 49% | COREYHAIM | 9 | "License to Drive" actor who played younger brother Sam in the 1987 vampire movie "The Lost Boys": 2 wds. |
| 48% | JOHNGOODMAN | 11 | "The Conners" actor who plays Papa Smurf in "Smurfs": 2 wds. |
| 48% | TOMHANKS | 8 | Actor who plays Josh Baskin in the movie "Big": 2 wds. |
| 48% | TBONE | 5 | Burnett who won four Grammys for the "O Brother, Where Art Thou?" soundtrack: 2 wds. |
| 48% | WINSTONDUKE | 11 | "Black Panther" actor who plays stunt coordinator Dan Tucker in "The Fall Guy": 2 wds. |
| 48% | JASONPATRIC | 11 | "Sleepers" actor who played older brother Michael in "The Lost Boys": 2 wds. |
| 47% | KIRKDOUGLAS | 11 | "Spartacus" actor who played Doc Holliday in 1957's "Gunfight at the O.K. Corral": 2 wds. |
| 47% | PAULDANO | 8 | "The Batman" actor who played twin brothers in 2007's "There Will Be Blood": 2 wds. |
| 46% | STEVECARELL | 11 | "The Big Short" actor who played the title boy's father in "Beautiful Boy": 2 wds. |
| 46% | BENEDICTWONG | 12 | "Doctor Strange" actor who plays a master of the mystic arts in 24-Across (2 wds.) |
| 46% | JOHNGOODMAN | 11 | Actor who plays Dan Conner on "The Conners" (2 wds.) |
| 46% | JOSHBROLIN | 10 | Actor who plays the fixer in 18-Across: 2 wds. |
| 46% | EWANMCGREGOR | 12 | "Christopher Robin" actor who plays Dan Torrance in the 2019 film adaptation of 37-Across (2 wds.) |
| 46% | FREDHECHINGER | 13 | "Gladiator II" actor who plays Kraven's half-brother, the Chameleon, in "Kraven the Hunter": 2 wds. |
| 46% | MARKRUFFALO | 11 | Actor who played the Hulk in the Avengers movies: 2 wds. |
| 46% | HUGHJACKMAN | 11 | Actor who played Wolverine in the "X-Men" series: 2 wds. |
| 46% | MICHAELKEATON | 13 | Actor who plays Vulture, the villain in 16-Across: 2 wds. |
| 46% | JASONMOMOA | 10 | Actor who plays "Aquaman" in the movie "Aquaman": 2 wds. |
| 46% | JIMPARSONS | 10 | "The Big Bang Theory" actor who played Michael in "The Boys in the Band": 2 wds. |
| 46% | RAYBOLGER | 9 | Actor who played the Scarecrow in "The Wizard of Oz": 2 wds. |
| 46% | TOMHANKS | 8 | Actor who played Elvis's manager in the biopic "Elvis": 2 wds. |
| 45% | CHACECRAWFORD | 13 | Actor who plays the key male character in "Gossip Girl": 2 wds. |
| 45% | BRYANCRANSTON | 13 | "Trumbo" actor who plays the owner of the Big Top Mall in "The One and Only Ivan" (2 wds.) |