| 100% | JUSTINTHEROUX | 13 | "The Girl on the Train" actor who plays Mel Wulf in "On the Basis of Sex" (2 wds.) |
| 70% | ARMIEHAMMER | 11 | "Call Me By Your Name" actor who plays Martin Ginsburg in "On the Basis of Sex" (2 wds.) |
| 58% | LAURAPREPON | 11 | "The Girl on the Train" actress, who played Donna Pinciotti in "That 70's Show": 2 wds. |
| 58% | EMILYBLUNT | 10 | "The Girl on the Train" star who plays the title character in "Mary Poppins Returns": 2 wds. |
| 57% | FELICITYJONES | 13 | Actress who played Ruth Bader Ginsburg in the film "On the Basis of Sex": 2 wds. |
| 56% | CAILEESPAENY | 12 | "On the Basis of Sex" actress who plays Elvis Presley's wife in "Priscilla" (2 wds.) |
| 56% | CAILEESPAENY | 12 | "On the Basis of Sex" actress who plays an aspiring photojournalist in "Civil War" (2 wds.) |
| 54% | DANIELKALUUYA | 13 | Actor who plays Slim, one of the title characters on the run in 2019's "Queen & Slim": 2 wds. |
| 53% | VICTAYBACK | 10 | Actor who played diner owner Mel on the sitcom "Alice": 2 wds. |
| 53% | ANTHONYRAMOS | 12 | "In the Heights" actor who plays Noah Diaz in "Transformers: Rise of the Beasts": 2 wds. |
| 53% | SAMWORTHINGTON | 14 | "Hacksaw Ridge" actor who plays Jake Sully in "Avatar: The Way of Water": 2 wds. |
| 52% | FRANKIEMUNIZ | 12 | Actor who played child prodigy Malcolm on "Malcolm in the Middle": 2 wds. |
| 52% | EDDIEREDMAYNE | 13 | "The Danish Girl" actor who plays Tom Hayden in "The Trial of the Chicago 7" (2 wds.) |
| 52% | EDDIEREDMAYNE | 13 | "The Danish Girl" actor who plays Newt Scamander in "Fantastic Beasts: The Crimes of Grindelwald" (2 wds.) |
| 52% | FELICITYJONES | 13 | "Rogue One" actress who plays Ruth Bader Ginsburg in "On the Basis of Sex" (2 wds.) |
| 52% | SAMROCKWELL | 11 | Actor who plays the father in the 2015 remake of 18-Across: 2 wds. |
| 52% | DANAYKROYD | 10 | "Ghostbusters" actor who plays the Scarecrow in "Legends of Oz": 2 wds. |
| 51% | KENNETHCHOI | 11 | Actor who played Chester Ming on "The Wolf of Wall Street" and portrays the role of Judge Lance Ito in "American Crime Story" : 2 wds. |
| 51% | RAYBOLGER | 9 | Actor who played the Scarecrow in "The Wizard of Oz": 2 wds. |
| 51% | OMARIHARDWICK | 13 | "Army of the Dead" actor who plays an FBI agent in "The Mother": 2 wds. |
| 51% | ANTHONYHOPKINS | 14 | Welsh-born actor who played Hannibal Lecter in "The Silence of the Lambs": 2 wds. |
| 51% | ALANRITCHSON | 12 | "Reacher" actor who plays the father of a critically ill girl in "Ordinary Angels" (2 wds.) |
| 51% | SAMWORTHINGTON | 14 | "The Shack" actor who plays Jake Sully in "Avatar: The Way of Water" (2 wds.) |
| 51% | SPENCERTRACY | 12 | Actor who played the lawyer based on Clarence Darrow in 32-Across: 2 wds. |
| 50% | FREDSAVAGE | 10 | Actor who played Kevin Arnold in the original version of 36-Across and is coproducing the reboot: 2 wds. |
| 50% | WAGNERMOURA | 11 | "Narcos" actor who plays reporter Dan Velasquez on the Apple TV+ crime thriller "Shining Girls": 2 wds. |
| 50% | EMILYBLUNT | 10 | "Jungle Cruise" actress who starred in 2016's "The Girl on the Train": 2 wds. |
| 50% | PETERUSTINOV | 12 | Actor who played Hercule Poirot in the 1978 film "Death on the Nile": 2 wds. |
| 50% | FREDRICMARCH | 12 | Actor who played the lawyer based on William Jennings Bryan in 32-Across: 2 wds. |
| 50% | KENNETHBRANAGH | 14 | "Tenet" actor who plays Hercule Poirot in "Death on the Nile": 2 wds. |