| 100% | RALPHFIENNES | 12 | "The Grand Budapest Hotel" actor who plays Professor Moriarty in "Holmes & Watson": 2 wds. |
| 62% | JUDELAW | 7 | "Alfie" actor who played Dr. Watson in the movie "Sherlock Holmes": 2 wds. |
| 59% | JUDELAW | 7 | Actor who plays John Watson in the 2009 film "Sherlock Holmes" (2 wds.) |
| 59% | ZUCCO | 5 | George —, Manchester-born actor who played Professor Moriarty in 1939 film drama The Adventures of Sherlock Holmes |
| 59% | WILLFERRELL | 11 | "Anchorman" actor who plays Sherlock Holmes in the upcoming movie "Holmes & Watson": 2 wds. |
| 55% | JACKBLACK | 9 | Actor who plays Professor Shelly Oberon in "Jumanji: Welcome to the Jungle" (2 wds.) |
| 53% | ADRIENBRODY | 11 | "The Pianist" actor who appeared in "The Grand Budapest Hotel": 2 wds. |
| 52% | EDDIEMURPHY | 11 | Actor who played Mama and Granny Klump in "The Nutty Professor": 2 wds. |
| 52% | JUDELAW | 7 | Actor who plays 22-Across/41-Across in the 2009 film "Sherlock Holmes" (2 wds.) |
| 50% | JOSHBROLIN | 10 | Actor who plays the fixer in 18-Across: 2 wds. |
| 50% | MICHAELKEATON | 13 | Actor who plays Vulture, the villain in 16-Across: 2 wds. |
| 50% | MARKRUFFALO | 11 | Actor who played the Hulk in the Avengers movies: 2 wds. |
| 50% | HUGHJACKMAN | 11 | Actor who played Wolverine in the "X-Men" series: 2 wds. |
| 50% | JASONMOMOA | 10 | Actor who plays "Aquaman" in the movie "Aquaman": 2 wds. |
| 50% | ALANRICKMAN | 11 | Actor who played Professor Snape and was a misunderstood character in "Harry Potter" series: 2 wds. |
| 49% | EZRAMILLER | 10 | Actor who plays the title character in the new movie "The Flash": 2 wds. |
| 49% | SAMROCKWELL | 11 | Actor who plays the father in the 2015 remake of 18-Across: 2 wds. |
| 49% | EDWARDNORTON | 12 | Actor who played the magician Eisenheim in the 2006 film "The Illusionist": 2 wds. |
| 49% | CHANNINGTATUM | 13 | Actor who plays one of the studio's stars in 18-Across: 2 wds. |
| 49% | ALEXKARPOVSKY | 13 | Actor who plays Craig in the psychological thriller web TV series, "Homecoming": 2 wds. |
| 49% | JAMESHANDY | 10 | Actor who played the exterminator in the 1995 fantasy adventure film "Jumanji": 2 wds. |
| 49% | ROGERWARD | 9 | Actor who played Fred "Fifi" Macaffee in the 1979 film "Mad Max": 2 wds. |
| 49% | SPENCERTRACY | 12 | Actor who played the lawyer based on Clarence Darrow in 32-Across: 2 wds. |
| 49% | CHACECRAWFORD | 13 | Actor who plays the key male character in "Gossip Girl": 2 wds. |
| 49% | RAYBOLGER | 9 | Actor who played the Scarecrow in "The Wizard of Oz": 2 wds. |
| 49% | MICHAELDOUGLAS | 14 | Actor who played Dan Gallagher, the husband, in "Fatal Attraction": 2 wds. |
| 49% | TOMHANKS | 8 | Actor who played Elvis's manager in the biopic "Elvis": 2 wds. |
| 49% | EDDIEMURPHY | 11 | "Coming 2 America" actor who played seven roles in the 1996 hit film "The Nutty Professor": 2 wds. |
| 49% | TOMELLIS | 8 | Actor who plays the titular role in the fantasy series "Lucifer": 2 wds. |
| 49% | TOMCRUISE | 9 | Actor who plays agent Ethan Hunt in the "Mission: Impossible" movies: 2 wds. |