| 100% | ELISABETHMOSS | 13 | "The Handmaid's Tale" actress who plays the writer Shirley Jackson in "Shirley" (2 wds.) |
| 71% | MCKENNAGRACE | 12 | "The Handmaid's Tale" actress who plays Phoebe Spengler in "Ghostbusters: Frozen Empire": 2 wds. |
| 69% | ELISABETHMOSS | 13 | "Mad Men" actress who plays Offred in "The Handmaid's Tale": 2 wds. |
| 68% | SAMIRAWILEY | 11 | "Orange Is the New Black" actress who plays Moira in "The Handmaid's Tale" (2 wds.) |
| 67% | ELISABETHMOSS | 13 | Golden Globe-winning "The Handmaid's Tale" actress who plays Masha in the 2018 film "The Seagull" (2 wds.) |
| 65% | MCKENNAGRACE | 12 | "The Handmaid's Tale" actress who plays Phoebe Spengler in 3-Down/4-Down (2 wds.) |
| 65% | ELISABETHMOSS | 13 | "Mad Men" actress who plays Ofglen in "The Handmaid's Tale" (2 wds.) |
| 61% | ELISABETHMOSS | 13 | "The Handmaid's Tale" actress who plays newspaper archivist Kirby Mazrachi on "Shining Girls": 2 wds. |
| 60% | MAXMINGHELLA | 12 | "The Handmaid's Tale" actor who plays studio executive Irving Thalberg in "Babylon" (2 wds.) |
| 59% | OTFAGBENLE | 10 | "The Handmaid's Tale" actor who plays a S.H.I.E.L.D. agent in 39-Across (2 wds.) |
| 59% | SAMIRAWILEY | 11 | "Orange Is the New Black" actress who plays Moira Strand on "The Handmaid's Tale" (2 wds.) |
| 59% | PENELOPEANN | 11 | With 50-Across, "Carlito's Way" actress who plays the First Lady in 16-Across: 2 wds. |
| 58% | ELISABETHMOSS | 13 | "The Handmaid's Tale" star who won the 2017 Emmy Award for Outstanding Lead Actress in a Drama Series (2 wds.) |
| 58% | BLAKELIVELY | 11 | Actress who plays the "It Girl" in "Gossip Girl": 2 wds. |
| 58% | ELISABETHMOSS | 13 | "The Handmaid's Tale" actress who plays Detective Robin Griffin on "Top of the Lake" and "Top of the Lake: China Girl" (2 wds.) |
| 58% | JOSEPHFIENNES | 13 | "Shakespeare in Love" actor who plays Commander Waterford in "The Handmaid's Tale": 2 wds. |
| 58% | SARAHPAULSON | 12 | "American Horror Story" actress who plays the title character in Netflix's "Ratched": 2 wds. |
| 58% | LIVTYLER | 8 | "Armageddon" actress who played the lead singer's girlfriend Faye in 34-Across: 2 wds. |
| 58% | JULIAROBERTS | 12 | "Pretty Woman" actress who played the title role in 2000's "Erin Brockovich": 2 wds. |
| 57% | KATHRYNHAHN | 11 | "Bad Moms" actress who plays the nosy neighbor Agnes in "WandaVision": 2 wds. |
| 57% | MARGARETATWOOD | 14 | "The Handmaid's Tale" writer who had a cameo as an Aunt in the Hulu adaptation of her novel (2 wds.) |
| 57% | LESLIEJONES | 11 | Actress who plays the mother of Prince Akeem's son in "Coming 2 America": 2 wds. |
| 57% | LAURADERN | 9 | Actress who plays Jennifer Fox in "The Tale" and has an Outstanding Lead Actress nomination for the 70th Emmys: 2 wds. |
| 57% | JOSEPHFIENNES | 13 | "Shakespeare in Love" actor who plays the Commander in the 2017 Hulu series "The Handmaid's Tale" (2 wds.) |
| 56% | AMANDASEYFRIED | 14 | "Ted 2" actress who plays Donna's daughter Sophie in the "Mamma Mia!" sequel: 2 wds. |
| 56% | RACHELMCADAMS | 13 | "Doctor Strange" actress who plays the title character's mom in 33-/49-Across: 2 wds. |
| 56% | SALLYHAWKINS | 12 | "The Shape of Water" actress who plays Willy Wonka's mother in "Wonka": 2 wds. |
| 56% | JANECURTIN | 10 | Actress who played Prymaat from the planet Remulak in 1993's "Coneheads": 2 wds. |
| 56% | KRISTENSCHAAL | 13 | "Bob's Burgers" actress who plays recurring character The Guide in "What We Do in the Shadows": 2 wds. |
| 56% | DEBBIEREYNOLDS | 14 | "The Singing Nun" actress who played the star's love interest in "Singin' in the Rain": 2 wds. |