| 100% | JERRYLEWIS | 10 | "The Nutty Professor" (1963) half of a classic comedy duo (2 wds.) |
| 70% | DEANMARTIN | 10 | "Ocean's 11" (1960) half of a classic comedy duo (2 wds.) |
| 61% | MEARA | 5 | Half of a classic comedy duo |
| 50% | KENNYROGERS | 11 | Male half of the duo that sang 16-/40-Across: 2 wds. |
| 50% | DOLLYPARTON | 11 | Female half of the duo that sang 16-/40-Across: 2 wds. |
| 50% | KANYEWEST | 9 | One half of the rap duo who performed 11-Down: 2 wds. |
| 50% | STANLAUREL | 10 | One of a classic comedy duo |
| 49% | DESI | 4 | Half of a classic TV duo |
| 49% | ANNEMEARA | 9 | Half of a longtime comedy duo |
| 48% | FROG | 4 | Half of a classic children’s-book duo |
| 48% | TOM | 3 | Half of a classic Hanna-Barbera cartoon duo |
| 46% | STRAIGHTMAN | 11 | Half of a comedy duo, perhaps |
| 46% | MEARA | 5 | Half of a well-known comedy duo |
| 46% | CHEECH | 6 | Half of a 1970s-'80s comedy duo |
| 45% | COSTELLO | 8 | Half of a 1940's-50's comedy duo |
| 45% | SIDEB | 5 | Second half of a record: 2 wds. |
| 45% | ACTTWO | 6 | Second half of a musical: 2 wds. |
| 44% | BSIDE | 5 | Lesser-known half of a record: 2 wds. |
| 44% | CHONG | 5 | Half of a comedy duo appearing in Scorsese's After Hours |
| 44% | BSIDE | 5 | Lesser half of a vinyl single: 2 wds. |
| 44% | ACTII | 5 | Second half of a play segment: 2 wds. |
| 44% | DONTTELL | 8 | Last half of a former US military policy involving gays: 2 wds. |
| 42% | OATES | 5 | Half of the duo that sang "Did It In A Minute" |
| 42% | FATLIP | 6 | Result of a punch to the mouth: 2 wds. |
| 42% | BEAST | 5 | Half of a Disney duo, with "the" |
| 42% | THEODD | 6 | With 33-Across, CBS remake of a classic sitcom about mismatched roommates: 2 wds. |
| 42% | RAISINGARIZONA | 14 | 1987 Coen brothers comedy about the kidnapping of a quintuplet: 2 wds. |
| 41% | DEARSANTA | 9 | Start of a letter to the North Pole: 2 wds. |
| 41% | JERRYLEWIS | 10 | "The Nutty Professor" star who received the Hersholt Humanitarian Award in 2009: 2 wds. |
| 41% | PITABREAD | 9 | The wrapping of a falafel sandwich: 2 wds. |