| 100% | SON | 3 | "The Orphan Master's ___" (Pulitzer-winning novel by Adam Johnson) |
| 62% | ADAM | 4 | "The Orphan Master's Son" Pulitzer winner Johnson |
| 57% | LESS | 4 | Novel by Andrew Sean Greer that won the Pulitzer Prize in 2018 |
| 57% | THEOVERSTORY | 12 | Novel by 30-Across that won the Pulitzer Prize for Fiction (2 wds.) |
| 55% | LESS | 4 | 2018 novel by Andrew Sean Greer that won the Pulitzer Prize for Fiction |
| 55% | THEGOOD | 7 | & 19A 1931 novel by Pearl Buck that won the Pulitzer Prize the following year |
| 55% | THEOVERSTORY | 12 | 2018 novel by 32-Across that won the Pulitzer Prize for Fiction (2 wds.) |
| 55% | OVERSTORY | 9 | "The ___," novel by Richard Powers that won the 2019 Pulitzer Prize for Fiction |
| 52% | NIGHT | 5 | "The ___ Watchman," 2020 novel by Louise Erdrich that won the 2021 Pulitzer Prize for Fiction |
| 51% | ADAM | 4 | "The Orphan Master's Son" novelist Johnson |
| 51% | ROAD | 4 | "The ___," 2006 novel by Cormac McCarthy featuring an unnamed protagonist that won the Pulitzer Prize for Fiction |
| 51% | AGE | 3 | Edith Wharton's Pulitzer winning novel "The ___ of Innocence" |
| 48% | GOLDFINCH | 9 | Pulitzer-winning novel by Donna Tartt, with "the" |
| 48% | SHEEP | 5 | "A Wild ____ Chase," 1982 novel by Haruki Murakami which won the Noma Literary Newcomer's prize |
| 46% | DEEPTHOUGHT | 11 | Computer in 1979 novel The Hitchhiker's Guide to the Galaxy by Douglas Adams |
| 45% | POSTCARDS | 9 | Novel by 29-Across that won the 1992 PEN/Faulkner Award for fiction |
| 45% | CUJO | 4 | 1981 novel by Stephen King that won the British Fantasy Award |
| 45% | AMERICANAH | 10 | Novel by Chimamanda Ngozi Adichie that won the 2013 National Book Critics Circle Award |
| 44% | ASBRAVEASYOU | 12 | 2016 novel by 30-Across that won the Kirkus Prize: 4 wds. |
| 44% | RASSELAS | 8 | Name by which Samuel Johnson's 1759 novel The Prince of Abissinia: A Tale is also known |
| 44% | GUN | 3 | The —, 1933 novel by C S Forester |
| 44% | SHIP | 4 | The —, 1943 novel by C S Forester |
| 44% | NARNIA | 6 | Setting of seven fantasy novels by C S Lewis published in the 1950s |
| 43% | ONEOFOURS | 9 | Pulitzer-winning novel by Willa Cather |
| 43% | BELOVED | 7 | 1987 Pulitzer-winning novel about the haunting of a formerly enslaved family's home |
| 43% | THEUNCONSOLED | 13 | 1995 novel by Kazuo Ishiguro for which he won the Cheltenham Prize: 2 wds. |
| 43% | ADAM | 4 | Novelist Johnson who won the 2012 Pulitzer Prize for fiction |
| 43% | LONESOMEDOVE | 12 | Western novel that won the 1986 Pulitzer Prize: 2 wds. |