| 100% | SEVEN | 5 | "The Secret ___," fictional group of child detectives created by Enid Blyton |
| 46% | THEFAMOUSFIVE | 13 | Series of children's novels written by Enid Blyton featuring the adventures of a group of young children and their dog Timmy: 3 wds. |
| 44% | HERCULEPOIROT | 13 | Fictional Belgian detective created by Agatha Christie who is also one of the most famous and long-running characters: 2 wds. |
| 37% | BARR | 4 | American writer of mystery novels, Nevada ___ who created the fictional detective, Anna Pigeon |
| 36% | NANCYDREW | 9 | Fictional girl detective who first appeared in 1930 novel The Secret of the Old Clock by Carolyn Keene |
| 36% | DOCSAVAGE | 9 | Fictional character created by Lester Dent who first appeared in 1933 pulp novel The Man of Bronze |
| 36% | JERRY | 5 | Fictional sitcom within a sitcom created by the titular character of "Seinfeld" with his friend, George Costanza |
| 35% | ENID | 4 | Children's author Blyton of "The Secret Seven" |
| 35% | JANEMARPLE | 10 | Fictional detective created by Agatha Christie: 2 wds. |
| 35% | PHILIPMARLOWE | 13 | Fictional detective created by Raymond Chandler: 2 wds. |
| 35% | MIKEHAMMER | 10 | Fictional detective created by Mickey Spillane: 2 wds. |
| 35% | XMEN | 4 | Group of mutants created by 27-Down: Hyph. |
| 35% | CHAIN | 5 | Group of businesses owned by the same company |
| 34% | SHERLOCKHOLMES | 14 | Fictional detective created by Arthur Conan Doyle: 2 wds. |
| 33% | IRAQ | 4 | Country created by the Treaty of Sèvres, 1920 |
| 33% | EEC | 3 | Trade org. created by the Treaty of Rome |
| 33% | ODIE | 4 | Yellow dog created by the creator of "Garfield" |
| 33% | EEC | 3 | Org. created by the 1957 Treaty of Rome |
| 33% | IIS | 3 | Group of Internet servers created by Microsoft for use with Windows NT family |
| 33% | REACHER | 7 | Private investigator Jack created by the novelist Lee Child |
| 33% | ILO | 3 | U.N. agcy. created by the Treaty of Versailles |
| 33% | EEC | 3 | Trade assn. created by the Treaty of Rome (1957) |
| 33% | FANTASTICFOUR | 13 | Group of superheroes created by Jack Kirby and Stan Lee (2 wds.) |
| 33% | THEXMEN | 7 | Group of superheroes created by Jack Kirby and Stan Lee (2 wds.) |
| 33% | THEAVENGERS | 11 | Group of superheroes created by Jack Kirby and Stan Lee (2 wds.) |
| 33% | BLYTON | 6 | Children's author Enid, created The Famous Five |
| 32% | EEOC | 4 | U.S. agency created by the Civil Rights Act of 1964 |
| 32% | GAP | 3 | Space created by the loss of a baby tooth, e.g. |
| 32% | CHERUB | 6 | The type of angel represented by a chubby child |