| 100% | EVERYTHING | 10 | "The Theory of ___," book by Stephen Hawking based on a series of lectures given at Cambridge University |
| 44% | PLAZA | 5 | "Eloise at the ___" (Disney film based on a series of Kay Thompson children's novels) |
| 42% | NOW | 3 | "The Spectacular ___," romantic comedy film which was based on a book of the same name by Tim Tharp |
| 40% | SWEETBITTER | 11 | American drama TV series starring Ella Purnell which is based on a novel of the same name by Stephanie Danler |
| 40% | EVERYTHING | 10 | "The Theory of ___," biographical romantic drama film from 2014 based on the life of Stephen Hawking |
| 39% | INTOTHEWILD | 11 | 2007 film starring Emile Hirsch based on a book of the same name by Jon Krakauer set in the Alaskan wilderness: 3 wds. |
| 39% | THEALIENIST | 11 | American period drama TV series starring Dakota Fanning which is based on a novel of the same name by Caleb Carr: 2 wds. |
| 39% | SPY | 3 | "The ___," Netflix series based on the life of a Mossad agent directed by Gideon Raff and starring Sacha Baron Cohen |
| 39% | JUSTIFIED | 9 | FX show based on a series of Elmore Leonard books |
| 39% | HANNIBAL | 8 | NBC show based on a series of Thomas Harris books |
| 39% | SHERLOCK | 8 | BBC show based on a series of Arthur Conan Doyle books |
| 39% | LILIES | 6 | "Water ___," a series of oil paintings by French impressionist Claude Monet which are on display at museums across the world |
| 39% | ALTEREDCARBON | 13 | American dystopian sci-fi TV series starring Joel Kinnaman which is based on a novel of the same name by Richard K. Morgan: 2 wds. |
| 39% | BRIEFHISTORYOF | 14 | "A ___Time," 1988 book on cosmology by Stephen Hawking which is written in a non-technical way for the masses: 3 wds. |
| 39% | TRUEBLOOD | 9 | HBO show based on a series of Charlaine Harris books: 2 wds. |
| 38% | INCOLDBLOOD | 11 | *1967 movie based on a series of New Yorker articles by Truman Capote |
| 38% | WITCHER | 7 | "The ___," 2019 TV series based on the book series by Andrzej Sapkowski which was adapted into a video game |
| 38% | MORMON | 6 | The Book of __, musical based on a US religion |
| 38% | MASK | 4 | "The ___," 1994 Jim Carrey movie that is based on a comic book series by Dark Horse Comics |
| 38% | GAMEOFTHRONES | 13 | HBO show based on a series of George R.R. Martin books: 3 wds. |
| 38% | MEETMEINSTLOUIS | 15 | *1944 movie based on a series of New Yorker short stories by Sally Benson |
| 38% | WATCHMEN | 8 | American satirical and dystopian superhero film directed by Zack Snyder which is based on a DC Comics limited series of the same name |
| 38% | KATHRYNHAHN | 11 | "WandaVision" actress who plays advice columnist Clare Pierce in the Hulu series "Tiny Beautiful Things," based on a book by 30-Across (2 wds.) |
| 37% | DOROTHY | 7 | "___ at Forty," song by Cursive based on a famous literary character from "The Wonderful Wizard of Oz" |
| 37% | GIANTS | 6 | "On the Shoulders of ___," scientific book that was compiled and edited by Stephen Hawking |
| 37% | STAND | 5 | "___ by Me," a coming-of-age drama based on the Stephen King novella "The Body" |
| 37% | TEEN | 4 | "___ Wolf," supernatural drama TV series based on the 1985 film of the same name, about a youngster who is bitten by a werewolf |
| 36% | DOME | 4 | "Under the ___" (TV series based on a Stephen King novel) |
| 36% | FAME | 4 | TV series based on the 1980 film of the same name about a group of students at a fictional school for the performing arts |
| 36% | FARGO | 5 | TV series based on a 1996 film by the Coen brothers |