| 100% | DILLON | 6 | "There's Something About Mary" co-star |
| 84% | DIAZ | 4 | Cameron, star of There's Something About Mary |
| 71% | DIAZ | 4 | "There's Something About Mary" actress Cameron |
| 67% | MINUTE | 6 | 7-___ Abs (program featured in "There's Something About Mary") |
| 65% | DIAZ | 4 | Cameron —, actress who starred in the 1998 film comedy There's Something About Mary |
| 63% | BRETTFAVRE | 10 | Former NFL quarterback who has a cameo in "There's Something About Mary" (2 wds.) |
| 62% | BRETT | 5 | With 33-Across, former Packers quarterback who made a cameo in "There's Something About Mary" |
| 56% | HALO | 4 | Something about Mary? |
| 55% | THERES | 6 | "___ Something About Mary" |
| 55% | THERES | 6 | "____ Something About Mary" |
| 52% | MARY | 4 | "There's Something About ___" (Cameron Diaz movie) |
| 51% | MARY | 4 | "There's Something About ___," 1998 romcom directed by the Farrellys, starring Cameron Diaz which is also one of the highest grossing rom coms of all times |
| 50% | AROSE | 5 | "There's Something About ___ (That Reminds Me of You)" |
| 48% | ABOUT | 5 | "There's Something ___ Mary" (Cameron Diaz movie) |
| 47% | REISER | 6 | Hunt's "Mad About You" co-star |
| 47% | ALSO | 4 | "There's something else I wanted to talk about ..." |
| 45% | TED | 3 | Mary's "Ink" co-star |
| 43% | EZIO | 4 | Mary's "South Pacific" co-star |
| 43% | ALT | 3 | Prefix for a music genre that indicates there's something different about it |
| 43% | ABOUTMARY | 9 | "There's Something ___," 1998 comedy starring Cameron Diaz and Ben Stiller: 2 wds. |
| 42% | MIA | 3 | Dustin's co-star in "John and Mary" |
| 42% | REISER | 6 | Hunt's co-star on "Mad About You" |
| 41% | SUREBET | 7 | There's no doubt about it |
| 41% | FILET | 5 | There's no bones about it |
| 40% | ADO | 3 | There's much about nothing |
| 40% | TEAPOT | 6 | Something's brewing there |
| 40% | UMA | 3 | Janeane's co-star in "The Truth About Cats & Dogs" |
| 40% | EXTRAPOINT | 10 | Something about which you might say "It's good!" |
| 39% | IDOIDO | 6 | 1966 musical co-starring Mary Martin |
| 39% | IHAVETOASK | 10 | "OK, there's something puzzling me …" |