| 100% | JUSTINHARTLEY | 13 | "This Is Us" actor who played Fox Crane on the soap opera "Passions" (2 wds.) |
| 58% | MARKCONSUELOS | 13 | "Riverdale" actor who played Mateo Santos on the soap opera "All My Children" (2 wds.) |
| 55% | CHRISSULLIVAN | 13 | "The Knick" actor who plays Toby Damon on "This Is Us": 2 wds. |
| 55% | JUSTINHARTLEY | 13 | "The Young and the Restless" actor who plays Kevin Pearson on "This Is Us": 2 wds. |
| 52% | JUSTINHARTLEY | 13 | "This Is Us" actor who plays Colter Shaw on "Tracker" (2 wds.) |
| 51% | CARLOSVALDES | 12 | Actor who plays Cisco Ramon on "The Flash" which is a part of the Arrowverse: 2 wds. |
| 51% | ANTHONYMACKIE | 13 | Actor who plays Falcon in the Marvel Cinematic Universe and has been on "Black Mirror": 2 wds. |
| 50% | TIMROTH | 7 | "Pulp Fiction" actor who played Dr. Cal Lightman on the Fox series "Lie To Me": 2 wds. |
| 50% | EWANMCGREGOR | 12 | Actor who plays the protagonist in "Christopher Robin" which is a fantasy film based on "Winnie-the-Pooh": 2 wds. |
| 49% | JOSHCHARLES | 11 | Actor who played attorney Will Gardner on "The Good Wife": 2 wds. |
| 49% | NICHOLASHOULT | 13 | Actor who plays the protagonist in "Jack the Giant Slayer," which is a fantasy film based on British fairy tales: 2 wds. |
| 49% | ROBERTSEAN | 10 | With 25-Across, actor who played Dr. James Wilson (based on 47-Across) on the Fox series "House": 2 wds. |
| 49% | DANIELKALUUYA | 13 | Actor who plays W'Kabi in the Marvel Cinematic Universe and has been on "Black Mirror": 2 wds. |
| 48% | JEFFDANIELS | 11 | Actor who won a 2013 Emmy for playing Will McAvoy, the anchor and managing editor on 37-Across: 2 wds. |
| 48% | LIEVSCHREIBER | 13 | "Spotlight" actor who has been nominated for three Emmys for playing the title role on 43-Across: 2 wds. |
| 47% | SETHROGEN | 9 | "The Studio" actor who plays Sylvia's friend Will on "Platonic": 2 wds. |
| 47% | ROBERTREDFORD | 13 | "The Sting" actor who played the love interest of Barbra Streisand's character in 1973's "The Way We Were": 2 wds. |
| 47% | JASONLEE | 8 | "My Name Is Earl" actor who plays the president's brother on "The Residence": 2 wds. |
| 47% | KELSEYGRAMMER | 13 | Actor who played Dr. Frasier Crane on "Frasier": 2 wds. |
| 47% | ALEXKARRAS | 10 | Actor who played the adoptive father on "Webster": 2 wds. |
| 47% | EMMANUELLEWIS | 13 | Actor who played the title character on "Webster": 2 wds. |
| 47% | RACHELHILSON | 12 | "This Is Us" actress who plays Victor's friend Mia in the Hulu teen drama "Love, Victor": 2 wds. |
| 46% | PEDROPASCAL | 11 | "The Mandalorian" actor who plays Joel on the HBO series "The Last of Us" (2 wds.) |
| 46% | NCUTIGATWA | 10 | "Sex Education" actor who will play the Fifteenth Doctor on "Doctor Who" (2 wds.) |
| 46% | VICTAYBACK | 10 | Actor who played diner owner Mel on the sitcom "Alice": 2 wds. |
| 46% | SEANGIAMBRONE | 13 | Actor who plays the geeky boy, Adam, on 18-Across: 2 wds. |
| 46% | PEDROPASCAL | 11 | "The Mandalorian" actor who plays Joel on the 2023 HBO series "The Last of Us" (2 wds.) |
| 46% | FREDRICMARCH | 12 | Actor who played the lawyer based on William Jennings Bryan in 32-Across: 2 wds. |
| 46% | JOSHUAJACKSON | 13 | Actor who played Pacey on the 1998-2003 teen drama "Dawson's Creek": 2 wds. |
| 46% | PATRICKSTEWART | 14 | Actor who played Captain Jean-Luc Picard on "Star Trek: The Next Generation": 2 wds. |