| 100% | BILLPAXTON | 10 | "Twister" actor who plays astronaut Fred Haise in "Apollo 13" (2 wds.) |
| 71% | KEVINBACON | 10 | "Footloose" actor who plays astronaut Jack Swigert in "Apollo 13" (2 wds.) |
| 61% | TOMHANKS | 8 | "Sully" actor who played real-life astronaut Jim Lovell in the 1995 film "Apollo 13": 2 wds. |
| 59% | TOMHANKS | 8 | "A Beautiful Day in the Neighborhood" actor who plays astronaut Jim Lovell in the docudrama about failed 1970 lunar mission Apollo 13 (2 wds.) |
| 58% | ROGERWARD | 9 | Actor who played Fred "Fifi" Macaffee in the 1979 film "Mad Max": 2 wds. |
| 58% | EDHARRIS | 8 | "The Hours" actor who played Flight Director Gene Kranz in "Apollo 13": 2 wds. |
| 58% | KEVINBACON | 10 | "Footloose" actor who played Command Module Pilot Jack Swigert in "Apollo 13": 2 wds. |
| 57% | TOMHANKS | 8 | "Philadelphia" actor who played Commander Jim Lovell in 1995's "Apollo 13": 2 wds. |
| 56% | GARYSINISE | 10 | "Forrest Gump" actor who played grounded Command Module Pilot Ken Mattingly in "Apollo 13": 2 wds. |
| 55% | RUTGERHAUER | 11 | "Ladyhawke" actor who played replicant Roy Batty in 13-Across: 2 wds. |
| 54% | EDHARRIS | 8 | "Snowpiercer" actor who played real-life astronaut John Glenn in the the 1983 film "The Right Stuff": 2 wds. |
| 53% | DYLANMINNETTE | 13 | Actor who plays Clay Jensen in the Netflix show "13 Reasons Why": 2 wds. |
| 53% | EDHARRIS | 8 | "The Right Stuff" actor who plays flight director Gene Kranz in "Apollo 13" (2 wds.) |
| 52% | BRYANCRANSTON | 13 | "Breaking Bad" actor who played real-life astronaut Buzz Aldrin in the 1998 HBO miniseries "From the Earth to the Moon": 2 wds. |
| 52% | HARRISONFORD | 12 | "Star Wars" actor who played cop Rick Deckard in 13-Across: 2 wds. |
| 52% | JASONMOMOA | 10 | Actor who plays Aquaman in 30-Across: 2 wds. |
| 52% | BENAFFLECK | 10 | Actor who plays Batman in 30-Across: 2 wds. |
| 52% | BRUCEDERN | 9 | Actor who plays Woody Grant in "Nebraska": 2 wds. |
| 52% | CHARLIECOX | 10 | Actor who plays Daredevil in "The Defenders": 2 wds. |
| 52% | STEVECARELL | 11 | Actor who plays Donald Rumsfeld in "Vice": 2 wds. |
| 51% | CHACECRAWFORD | 13 | Actor who plays the key male character in "Gossip Girl": 2 wds. |
| 51% | KEVINBACON | 10 | Actor who plays an FBI special agent in "Black Mass": 2 wds. |
| 51% | GABRIELMACHT | 12 | Actor who plays Harvey Specter, a top litigator in "Suits": 2 wds. |
| 51% | MICHAELKEATON | 13 | Actor who plays an alternate-universe Batman in "The Flash": 2 wds. |
| 51% | BENAFFLECK | 10 | Actor who plays this universe's Batman in "The Flash": 2 wds. |
| 51% | RAYBOLGER | 9 | Actor who played the Scarecrow in "The Wizard of Oz": 2 wds. |
| 51% | GEORGECLOONEY | 13 | Actor who played Danny Ocean in the Ocean's trilogy: 2 wds. |
| 51% | MICHAELDOUGLAS | 14 | Actor who played Dan Gallagher, the husband, in "Fatal Attraction": 2 wds. |
| 51% | STEPHENMOYER | 12 | Actor who played Bill Compton in HBO's "True Blood": 2 wds. |
| 51% | JOHNNYDEPP | 10 | Actor who played a vampire in 2012's "Dark Shadows": 2 wds. |