| 100% | MORGANFREEMAN | 13 | "Unforgiven" actor who narrated the scientific documentaries "March of the Penguins" and "Island of Lemurs: Madagascar": 2 wds. |
| 62% | ALECBALDWIN | 11 | "It's Complicated" actor who narrated the scientific documentaries "Journey to the Edge of the Universe" and "Frozen Planet": 2 wds. |
| 57% | JEREMYIRONS | 11 | "Dead Ringers" actor who narrated the scientific documentaries "The Last Lions" and "Life on Fire": 2 wds. |
| 55% | MORGANFREEMAN | 13 | Actor from "The Shawshank Redemption," who narrated the 2005 nature documentary "March of the Penguins": 2 wds. |
| 43% | ORLANDOBLOOM | 12 | Actor who starred in both the "Pirates of the Caribbean" and "Lord of the Rings" movie franchises: 2 wds. |
| 42% | JOSEPHCOTTEN | 12 | Actor who played a reporter and friend of the title character in 17-Across: 2 wds. |
| 42% | FESSPARKER | 10 | Actor who starred in the title roles of TV's "Davy Crockett" and "Daniel Boone": 2 wds. |
| 41% | MATTDAMON | 9 | Actor from "Saving Private Ryan," who narrated the 2010 political documentary "Inside Job": 2 wds. |
| 41% | PATTONOSWALT | 12 | "The King of Queens" actor who narrates 18-Across as the present-day adult Adam: 2 wds. |
| 41% | CHRISPRATT | 10 | Actor from "Passengers", who plays the role of Andy Dwyer in "Parks and Recreation": 2 wds. |
| 41% | SCOTTEASTWOOD | 13 | Actor who stars in "The Fate of the Furious", and whose father is Clint Eastwood: 2 wds. |
| 40% | MICHAELPENA | 11 | "Ant-Man" actor who plays Dora's father in "Dora and the Lost City of Gold": 2 wds. |
| 40% | JOSHTAYLOR | 10 | Actor who joined the cast of "Days of Our Lives" in 1977 as Chris Kositchek and later started playing Roman Brady: 2 wds. |
| 40% | DJIMONHOUNSOU | 13 | Actor who played the wizard Shazam in DC's "Shazam!" and Korath in Marvel's "Guardians of the Galaxy": 2 wds. |
| 40% | HUGHOBRIAN | 10 | Actor who starred in the title role of TV's "The Life and Legend of Wyatt Earp": 2 wds. |
| 40% | HARRISONFORD | 12 | "The Fugitive" actor who plays the title role in "Indiana Jones and the Dial of Destiny" (2 wds.) |
| 40% | PAULSCHNEIDER | 13 | Actor who played the role of Mark Brendanawicz in "Parks and Recreation", a character that appeared only in the first two seasons: 2 wds. |
| 40% | DONCHEADLE | 10 | Emmy-nominated actor who narrates the 2021 reboot of 32-Across (2 wds.) |
| 40% | JUSTINROILAND | 13 | American actor, who is the co-creator of "Rick and Morty", and also voices its two main characters : 2 wds. |
| 39% | ALECBALDWIN | 11 | Actor who plays Alan Hunley in the fifth and sixth installment of the "Mission: Impossible" series: 2 wds. |
| 39% | HARRISONFORD | 12 | Actor from 14a and 41a who also played the role of Han Solo in "Star Wars": 2 wds. |
| 39% | MARTINSTARR | 11 | Actor from "Freaks and Geeks", who plays the role of Bertram Gilfoyle in "Silicon Valley": 2 wds. |
| 39% | CHRISHEMSWORTH | 14 | "Rush" actor who plays Thor, the former king of Asgard, in "Thor: Love and Thunder": 2 wds. |
| 39% | DAVIDTENNANT | 12 | Scottish actor who played Barty Crouch, Jr. in "Harry Potter and the Goblet of Fire": 2 wds. |
| 39% | PETERDINKLAGE | 13 | Actor who plays Tyrion Lannister in "Game of Thrones," and has an Outstanding Supporting Actor nomination for the 70th Emmys: 2 wds. |
| 39% | PAULGIAMATTI | 12 | "Cinderella Man" and "Sideways" actor who turned down the role of Michael Scott on "The Office": 2 wds. |
| 39% | HARRISONFORD | 12 | "Indiana Jones and the Dial of Destiny" actor who plays Jimmy's mentor Paul on "Shrinking": 2 wds. |
| 39% | DONCHEADLE | 10 | "House of Lies" actor who narrates the 2021 version of 36-Across as the grown version of the 12-year-old lead character: 2 wds. |
| 38% | FREDSAVAGE | 10 | Actor who played Kevin Arnold in the original version of 36-Across and is coproducing the reboot: 2 wds. |
| 38% | BURTREYNOLDS | 12 | "Smokey and the Bandit" actor who turned down the role of Edward in 17-Across: 2 wds. |