| 100% | HUGOWEAVING | 11 | "V for Vendetta" actor who played Agent Smith in "The Matrix": 2 wds. |
| 63% | KYLEMACLACHLAN | 14 | Actor who is known for playing Special Agent Dale Cooper in the cult TV series "Twin Peaks": 2 wds. |
| 62% | TOMCRUISE | 9 | Actor who plays agent Ethan Hunt in the "Mission: Impossible" movies: 2 wds. |
| 59% | SIMONPEGG | 9 | Actor who plays technical field agent Benji Dunn in the "Mission: Impossible" series: 2 wds. |
| 58% | WEAVING | 7 | Actor Hugo __ plays Agent Smith in The Matrix |
| 57% | TOMMYLEEJONES | 13 | Actor who plays Agent K in the "Men in Black" films and who played football at Harvard (2 wds.) |
| 57% | JONFAVREAU | 10 | Actor who plays Happy Hogan in Marvel films, and has directed the pilot for "The Orville": 2 wds. |
| 57% | HUGO | 4 | Actor who played the role of Agent Smith in "The Matrix" |
| 56% | MATTSMITH | 9 | Actor who played Prince Philip in "The Crown" and had an Outstanding Supporting Actor nomination for the 70th Emmys: 2 wds. |
| 56% | CLARKGREGG | 10 | Actor who plays the character of Phil Coulson, a S.H.I.E.L.D agent in "Captain Marvel": 2 wds. |
| 55% | PETERDINKLAGE | 13 | Actor who plays Tyrion Lannister in "Game of Thrones," and has an Outstanding Supporting Actor nomination for the 70th Emmys: 2 wds. |
| 55% | COLINFIRTH | 10 | "The King's Speech" actor who plays secret agent Harry Hart in "Kingsman: The Golden Circle": 2 wds. |
| 55% | PATRICKSWAYZE | 13 | "Dirty Dancing" actor who played Vida the drag queen in the 1995 film "To Wong Foo, Thanks for Everything! Julie Newmar": 2 wds. |
| 54% | JAKELLOYD | 9 | Actor who played Anakin Skywalker in the film mentioned in 16a: 2 wds. |
| 54% | MIKECOLTER | 10 | Actor who plays Luke Cage in the Netflix miniseries "The Defenders": 2 wds. |
| 54% | TERRYCREWS | 10 | Actor who plays Detective Jeffords in the sitcom "Brooklyn Nine-Nine": 2 wds. |
| 54% | ADAMSANDLER | 11 | Actor who plays Howard Ratner in the 2019 movie "Uncut Gems": 2 wds. |
| 54% | BILLPAXTON | 10 | Actor who played Brock Lovett in the movie "Titanic": 2 wds. |
| 54% | TOMHANKS | 8 | Actor who plays Josh Baskin in the movie "Big": 2 wds. |
| 54% | JASONMOMOA | 10 | Actor who plays "Aquaman" in the movie "Aquaman": 2 wds. |
| 54% | SEBASTIANSTAN | 13 | "Avengers: Endgame" actor who plays CIA agent Nick in "The 355": 2 wds. |
| 54% | GEORGECLOONEY | 13 | Actor who played Danny Ocean in the Ocean's trilogy: 2 wds. |
| 54% | JOSHBROLIN | 10 | Actor who plays the fixer in 18-Across: 2 wds. |
| 53% | IANMCKELLEN | 11 | Actor who played the "old" Magneto in the "X-Men" series: 2 wds. |
| 53% | NICHOLASHOULT | 13 | Actor who played the "young" Beast in the "X-Men" series: 2 wds. |
| 53% | EDWARDNORTON | 12 | Actor who played the Hulk in 2008's "The Incredible Hulk": 2 wds. |
| 53% | EWANMCGREGOR | 12 | Actor who played 29-/32-Across in the 1990s and 2000s: 2 wds. |
| 53% | ALECGUINNESS | 12 | Actor who played 29-/32-Across in the 1970s and 1980s: 2 wds. |
| 53% | TOMELLIS | 8 | Actor who plays the titular role in the fantasy series "Lucifer": 2 wds. |
| 53% | NICOLASCAGE | 11 | Actor who plays Benjamin Franklin Gates in the "National Treasure" films: 2 wds. |