| 100% | SEANHAYES | 9 | "Will & Grace" actor who cohosts 41-Across: 2 wds. |
| 87% | JASONBATEMAN | 12 | "Ozark" actor who cohosts 41-Across: 2 wds. |
| 64% | SYDNEYPOLLACK | 13 | Actor who plays Will Truman's father on "Will & Grace" (2 wds.) |
| 64% | GREGORYHINES | 12 | Actor who plays Will Truman's boss on "Will & Grace" (2 wds.) |
| 62% | JAMIEDORNAN | 11 | Actor who will play Christian Grey in 18-Across: 2 wds. |
| 61% | MATTDAMON | 9 | Oscar-winning American actor who guest starred in NBC sitcom "Will & Grace": 2 wds. |
| 60% | JOHNTRAVOLTA | 12 | "Hairspray" actor who is a licensed pilot: 2 wds. |
| 60% | DANNYDEVITO | 11 | "Taxi" actor who is 4'10" tall: 2 wds. |
| 60% | MORGANFREEMAN | 13 | "Invictus" actor who is a licensed pilot: 2 wds. |
| 60% | ERICMCCORMACK | 13 | "Will & Grace" actor who's getting a Hollywood Walk of Fame star in 2018: 2 wds. |
| 59% | ALANCUMMING | 11 | "The Good Wife" actor who cohosted the 2015 Tony Awards: 2 wds. |
| 59% | CLINTEASTWOOD | 13 | Actor who portrayed gunslinger Will Munny in "Unforgiven": 2 wds. |
| 59% | ALPACINO | 8 | Actor who was Michael Corleone in "The Godfather": 2 wds. |
| 59% | FREDSAVAGE | 10 | Actor who played Kevin Arnold in the original version of 36-Across and is coproducing the reboot: 2 wds. |
| 59% | ASHTONKUTCHER | 13 | "That '70s Show" actor who has been played by 17-Across on "Saturday Night Live": 2 wds. |
| 59% | ALECBALDWIN | 11 | "Beetlejuice" actor who cohosted the 2010 Oscar ceremony with Steve Martin: 2 wds. |
| 59% | TARONEGERTON | 12 | "Kingsman: The Golden Circle" actor who stars in 41-Across: 2 wds. |
| 58% | JADENSMITH | 10 | Actor who appeared in "After Earth" with his father Will: 2 wds. |
| 58% | JOSHCHARLES | 11 | Actor who played attorney Will Gardner on "The Good Wife": 2 wds. |
| 58% | HARRISONFORD | 12 | "Cowboys & Aliens" actor who is a licensed pilot: 2 wds. |
| 58% | MARTINSHEEN | 11 | "Apocalypse Now" actor who was born Ramón Estévez: 2 wds. |
| 58% | DENNISQUAID | 11 | "The Substance" actor who is a licensed pilot: 2 wds. |
| 57% | TODDBRIDGES | 11 | Actor who played 32-Across: 2 wds. |
| 57% | GARYCOLEMAN | 11 | Actor who played 30-Across: 2 wds. |
| 57% | JAMESFRANCO | 11 | "The Disaster Artist" actor who cohosted the 2011 Oscar ceremony with Anne Hathaway: 2 wds. |
| 57% | MANDYPATINKIN | 13 | Actor who has been twice nominated for an Emmy for "Homeland": 2 wds. |
| 57% | BRUCEWILLIS | 11 | Emmy-winning "Moonlighting" actor who was born in Germany: 2 wds. |
| 57% | GARYCOLEMAN | 11 | "Diff'rent Strokes" actor who was 4'8" tall: 2 wds. |
| 57% | PETERDINKLAGE | 13 | "Game of Thrones" actor who is 4'4" tall: 2 wds. |
| 57% | JAMIEFOXX | 9 | "Django Unchained" actor who was born Eric Marlon Bishop: 2 wds. |