| 100% | IMIT | 4 | "You're looking at the one and only!" (2 wds.) |
| 50% | CLUE | 4 | You're looking at one |
| 50% | GRID | 4 | You're looking at one |
| 50% | ANGELINAJOLIE | 13 | "Maleficent" actress who voices an elephant in "The One and Only Ivan" (2 wds.) |
| 48% | TRUELOVE | 8 | The one and only |
| 48% | SHANIATWAIN | 11 | "You're Still the One" singer with three diamond albums: 2 wds. |
| 47% | FEDUP | 5 | At the end of one's rope: 2 wds. |
| 47% | ANGELINAJOLIE | 13 | "Maleficent" actress who voices the elephant Stella in "The One and Only Ivan": 2 wds. |
| 46% | SPLITENDS | 9 | Fraying at the tips of one's hair: 2 wds. |
| 46% | IMIT | 4 | "You're looking at the whole department" |
| 46% | NOTME | 5 | "You're looking at the wrong guy" |
| 45% | SAMROCKWELL | 11 | "Fosse/Verdon" actor who voices the gorilla Ivan in "The One and Only Ivan": 2 wds. |
| 45% | CHANNINGTATUM | 13 | "Magic Mike" actor who wrote the children's book "The One and Only Sparkella": 2 wds. |
| 45% | IVAN | 4 | The One and Only ___ (children's book about a gorilla) |
| 44% | ONEI | 4 | "You're the only ___ trust": 2 wds. |
| 44% | ANGELAMERKEL | 12 | First and only female chancellor of Germany (2005-present), and Time's 2015 Person of the Year: 2 wds. |
| 44% | ASANA | 5 | Yoga position like the ones at 9a and 15d that you will encounter during a day of practicing yoga |
| 44% | ANDRADAY | 8 | Singer who performed "Stand Up for Something" at the 2018 Oscars, accompanied by Common and various activists: 2 wds. |
| 44% | ONEI | 4 | "You're the only ___ trust.": 2 wds. |
| 43% | THESAME | 7 | One and ___: 2 wds. |
| 43% | ITSME | 5 | "I'm the one you're looking for" |
| 43% | BEA | 3 | "Can you not ___ bore at the party?": 2 wds. |
| 43% | ONEI | 4 | "You're the only ___ can trust": 2 wds. |
| 43% | AMI | 3 | "___ the only one?": 2 wds. |
| 43% | ONTOP | 5 | At the summit: 2 wds. |
| 43% | ONTOP | 5 | At the peak: 2 wds. |
| 43% | NSFW | 4 | "Don't look at this if you're in the office!": Abbr. |
| 43% | IDO | 3 | Words you expect to hear at the altar: 2 wds. |
| 43% | CHUCKCONNORS | 12 | Actor who was one of only 13 athletes to play in both the NBA and the MLB (2 wds.) |
| 42% | ONEI | 4 | "You're the ___ was looking for.": 2 wds. |