| 100% | TOOSOON | 7 | "You shouldn't be so quick to joke about that!" |
| 49% | ATE | 3 | You shouldn't be surprised that it could be up to a year since your pet anaconda last did this |
| 49% | FOODCOMA | 8 | Feeling of being so full that you don't want to move: 2 wds. |
| 45% | TMI | 3 | "LMAO you shouldn't be sharing that" |
| 43% | SEGA | 4 | Company based in Tokyo that is about to let you download "Humankind" |
| 42% | TOOSOON | 7 | “Oh, are we not allowed to joke about that yet?” |
| 41% | MEIR | 4 | Golda who said, “Don’t be so humble; you are not that great” |
| 40% | OHO | 3 | "So that's what you've been up to!" |
| 40% | TSK | 3 | "You shouldn't be doing that!" |
| 39% | TOOSOON | 7 | "You can't joke about that yet" |
| 39% | SORRY | 5 | "I am so ___ to hear that" |
| 38% | SPAM | 4 | Email that you probably shouldn't respond to |
| 38% | SORRY | 5 | "I am so ___ to hear that" (upset) |
| 38% | FORTHEFIRSTTIME | 15 | "Ladies and gentlemen, you are about to witness something extraordinary that has never been seen or attempted before!" (go to 34-Down) |
| 37% | GREMLINS | 8 | Movie about critters that you shouldn't get wet |
| 37% | ANTE | 4 | You have to be upfront about this |
| 37% | WAS | 3 | "___ that supposed to be a joke?" |
| 37% | IKNEW | 5 | "___ you were going to say that" |
| 37% | HEADOVERHEELS | 13 | 1985 Top 10 song by 42-Across that begins, "I wanted to be with you alone / And talk about the weather" (3 wds.) |
| 37% | WHYTHELONGFACE | 14 | “What are you so down about?” |
| 36% | YES | 3 | Answer to "Are you asleep?" that can't be true |
| 36% | STERN | 5 | To give someone a ___ look (indicate that you are serious) |
| 36% | FIRETRAP | 8 | Building that may be about to go up? |
| 36% | GENES | 5 | Cute reply to "Why are you so cute?" |
| 35% | SEE | 3 | "I told you that was going to happen" |
| 35% | THORN | 5 | Rose part that is out to hurt you |
| 35% | ERITU | 5 | Verdi aria that translates to "It was you" |
| 35% | AMEN | 4 | "___ to that!" ("You are so right!") |
| 35% | TAPE | 4 | What you shouldn't fight, according to an old maxim, when you're thinking about trading against the financial trend |
| 35% | RUDE | 4 | "You don't have to be a jerk about it!" |