| 100% | CHRISTINARICCI | 14 | "Z: The Beginning of Everything" actress who plays adult Misty on 50-Across (2 wds.) |
| 85% | CHRISTINARICCI | 14 | "Z: The Beginning of Everything" actress who plays adult Misty on "Yellowjackets" (2 wds.) |
| 56% | LAURENAMBROSE | 13 | "Six Feet Under" actress who plays adult Van on 50-Across (2 wds.) |
| 53% | ALEXISBLEDEL | 12 | "The Sisterhood of the Traveling Pants" actress who played daughter Rory on 14-Across: 2 wds. |
| 52% | SUSANSARANDON | 13 | Actress who played Louise, one of the title characters on the run in 1991's "Thelma & Louise": 2 wds. |
| 51% | ANNAFARIS | 9 | Actress who played Christy Plunkett on the first seven seasons of the CBS sitcom "Mom": 2 wds. |
| 51% | LISAWHELCHEL | 12 | Actress who played Blair on "The Facts of Life": 2 wds. |
| 51% | KIMFIELDS | 9 | Actress who played Tootie on "The Facts of Life": 2 wds. |
| 51% | MINDYCOHN | 9 | Actress who played Natalie on "The Facts of Life": 2 wds. |
| 51% | SUSIEESSMAN | 11 | Actress who plays the foul-mouthed wife of the main character's manager Jeff on "Curb Your Enthusiasm": 2 wds. |
| 51% | SARAHCHALKE | 11 | "Scrubs" actress who plays Kate Mularkey on the Netflix adaptation of 41-Across (2 wds.) |
| 51% | SONJASOHN | 9 | "The Wire" actress who plays Georgia Bureau of Investigation Deputy Director Amanda Wagner on 50-Across (2 wds.) |
| 51% | TOKSOLAGUNDOYE | 14 | Actress who plays the head of an Ivy League psychology department on "Frasier" (2 wds.) |
| 51% | NATALIEDORMER | 13 | "Game of Thrones" actress who played 32-Across on the CBS series "Elementary" (2 wds.) |
| 50% | CHARLOTTERAE | 12 | Actress who played Mrs. Garrett on "The Facts of Life": 2 wds. |
| 50% | LUCYLIU | 7 | Actress who played Joan (based on 47-Across) on the CBS series "Elementary": 2 wds. |
| 50% | JESSSALGUEIRO | 13 | Actress who plays Freddy's roommate on the Paramount+ reboot of "Frasier" (2 wds.) |
| 50% | LYNDACARTER | 11 | "Wonder Woman" actress who plays the President of the United States on "Supergirl" (2 wds.) |
| 50% | JULIECHRISTIE | 13 | "Shampoo" actress who played Lara in the 1965 film version of 19-Across: 2 wds. |
| 50% | ISABELSANFORD | 13 | Actress who played Louise Jefferson, the main character on the '70s sitcom "The Jeffersons" which is one of the longest-running sitcoms: 2 wds. |
| 49% | JAYNEATKINSON | 13 | "House of Cards" actress who plays the U.S. Attorney General on 34-Across (2 wds.) |
| 49% | RACHELMCADAMS | 13 | "The Notebook" actress who plays Ani Bezzerides on the latest season of "True Detective": 2 wds. |
| 49% | CLAIREFOY | 9 | Actress who plays Queen Elizabeth II on the first two seasons of "The Crown" (2 wds.) |
| 49% | FELICITYJONES | 13 | Actress who played Ruth Bader Ginsburg in the film "On the Basis of Sex": 2 wds. |
| 49% | OLIVIACOLMAN | 12 | Actress who played Queen Elizabeth II on two seasons of Netflix's "The Crown": 2 wds. |
| 49% | HELENEYORKE | 11 | "The Good Fight" actress who plays one of the siblings on 36-Across (2 wds.) |
| 49% | MOLLYSHANNON | 12 | "Divorce" actress who plays the mother of the siblings on 36-Across (2 wds.) |
| 49% | JANUARYJONES | 12 | Actress of the month who played Betty Francis on "Mad Men": 2 wds. |
| 49% | GINARODRIGUEZ | 13 | Actress who plays the title role on 15-Across: 2 wds. |
| 49% | MIAWASIKOWSKA | 13 | Actress who played the daughter of 14- and 32-Across in "The Kids Are All Right": 2 wds. |