| 100% | SPINNING | 8 | & 4A Machine patented by James Hargreaves in 1770 that wound yarn onto more than one spindle at a time |
| 27% | SEW | 3 | In 1790, England's Thomas Saint devised and patented a machine, improved many times since then, that would help people do this |
| 25% | NETPOSITIVE | 11 | That it catches fish in big batches rather than one at a time, e.g.? |
| 23% | LICE | 4 | More than one louse in a kid's hair |
| 23% | TAKESTWOTOTANGO | 15 | Requires more than one person, in a saying |
| 23% | EYRE | 4 | "Jane ___," a novel by Charlotte Bronte that has become one of the most famous novels of all time |
| 22% | TAB | 3 | You might have more than one open in a Web browser |
| 22% | SIN | 3 | Planting more than one kind of seed in a field, per Deuteronomy |
| 22% | ACTOR | 5 | One in a cast, at times |
| 22% | PRIZE | 5 | One of many in a claw machine |
| 22% | DEADHEAT | 8 | Race outcome when more than one runner finishes at the same time: 2 wds. |
| 21% | COMMA | 5 | One might appear many times in a long list |
| 21% | EBWHITE | 7 | Author whose last name's first letter, followed by the two initials that precede his last name, form a word in one of his most famous titles |
| 21% | MOO | 3 | Animal sound uttered by Doja Cat more than fifty times in a 2018 viral novelty song |
| 21% | SSNS | 4 | Figs. that Marnie Edgar has more than one of in Marnie |
| 20% | INCH | 4 | One of more than 1.6 million in a marathon |
| 20% | PANTS | 5 | Most everyone puts them on one leg at a time |
| 20% | TOOTH | 5 | John Lennon had one that sold for more than $31,000 at a 2011 auction (fittingly, to a dentist!) |
| 20% | DAY | 3 | "One ___ at a Time" (1970s sitcom rebooted in 2017) |
| 20% | DAY | 3 | "One ___ at a Time" (classic sitcom rebooted in 2017) |
| 20% | USE | 3 | By plugging in too many appliances at once the man blew a f___ |
| 20% | FAX | 3 | Office machine that was used more in the 1980s than today |
| 20% | ATL | 3 | 53-Down with more than 70 sts. that have a form of "Peachtree" in their names |
| 20% | DOS | 3 | More than one, in Madrid |
| 20% | STEP | 4 | One foot at a time |
| 20% | MONOGAMY | 8 | One spouse at a time |
| 20% | DANCE | 5 | One step at a time? |
| 20% | NEVER | 5 | How many times a one-point safety has occurred in the NFL |
| 20% | ONCE | 4 | At a time in the past |
| 20% | FRIDAYTHE13TH | 13 | This occurs at least once - and never more than three times - in a year |