| 100% | ROM | 3 | ___-com (movie like "My Best Friend's Wedding") |
| 73% | EVERETT | 7 | Rupert __, My Best Friend's Wedding actor |
| 60% | RUPERTEVERETT | 13 | "My Best Friend's Wedding" actor who plays older Patrick Hazelwood in "My Policeman" (2 wds.) |
| 58% | WEDDING | 7 | "My Best Friend's ___" (movie starring Julia Roberts) |
| 54% | KOOMSON | 7 | Dorothy —, author of novels My Best Friend's Girl and The Ice Cream Girls |
| 53% | BEST | 4 | "My ___ Friend's Wedding," 1997 movie starring Julia Roberts and Dermot Mulroney |
| 52% | THECARS | 7 | "My Best Friend's Girl" group |
| 52% | THECARS | 7 | "My Best Friend's Girl" band |
| 51% | THECARS | 7 | "My Best Friend's Girl" rock band |
| 51% | OCASEK | 6 | "My Best Friend's Girl" songwriter Ric |
| 51% | TRUEST | 6 | Like a best friend |
| 51% | CLOSEST | 7 | Like a best friend |
| 50% | LOYAL | 5 | Like man's best friend |
| 49% | FRIENDS | 7 | My Best __ Wedding, Julia Roberts romance |
| 48% | TRUEST | 6 | Like best friends |
| 48% | CLOSE | 5 | Like best friends |
| 48% | TIGHT | 5 | Like best friends |
| 48% | LOYAL | 5 | Like good friends |
| 48% | BEST | 4 | "My ___ Friend's Wedding" (1997 Julia Roberts rom-com) |
| 48% | NED | 3 | ___ Leeds (Peter Parker's best friend, in MCU movies) |
| 47% | OCASEK | 6 | Ric who wrote the hit song "My Best Friend's Girl" |
| 47% | TIGHT | 5 | Like the best of friends |
| 46% | LOYAL | 5 | Steadfast, like a good friend |
| 46% | TRUSTY | 6 | Reliable, like a good friend |
| 45% | NAMEDROP | 8 | Say "When I was with my good friend Barack last week ...," e.g. |
| 45% | BULLFROG | 8 | Jeremiah was a ___, was a good friend of mine |
| 45% | WEDDING | 7 | "My Best Friend's ___," 1997 romantic comedy starring Dermot Mulroney as sportswriter Michael O'Neal |
| 45% | ALPO | 4 | Best friend's dinner, maybe |
| 44% | ELFIN | 5 | Like Will Ferrell, in the best Christmas movie |
| 44% | BUDDIES | 7 | Best of friends, especially in a movie genre |