| 100% | SHELDON | 7 | ___ Cooper from "Big Bang Theory" who proposes to Amy Farrah Fowler at Princeton |
| 44% | MAYIM | 5 | ___ Bialik, actress who plays Amy Farrah Fowler in "The Big Bang Theory" |
| 44% | AMY | 3 | ___ Farrah Fowler, neuroscientist from "The Big Bang Theory" who has a Ph.D. in Neurobiology |
| 44% | HARP | 4 | Stringed instrument played by Amy Farrah Fowler on "The Big Bang Theory" |
| 42% | MAYIMBIALIK | 11 | She plays Dr. Amy Farrah Fowler—a neurobiologist—on CBS's "The Big Bang Theory": 2 wds. |
| 40% | AMY | 3 | ___ Farrah Fowler from "The Big Bang Theory" |
| 39% | AMY | 3 | Sheldon Cooper and ___ Farrah Fowler, popular fictional couple from "The Big Bang Theory" |
| 38% | AMY | 3 | ___ Farrah Fowler, character from "The Big Bang Theory" |
| 36% | JIM | 3 | ___ Parsons, multiple Emmy-winning openly gay actor of "The Big Bang Theory" who portrayed Sheldon Cooper |
| 35% | MAYIMBIALIK | 11 | "The Big Bang Theory" actress who earned a doctorate in neuroscience from 33-Down: 2 wds. |
| 35% | AMY | 3 | ___ Farrah Fowler, Mayim Bialik's character from "The Big Bang Theory" |
| 34% | SHELDON | 7 | Who Amy marries in The Big Bang Theory |
| 32% | MAYIMBIALIK | 11 | Actress who played young C.C. Bloom in the 1988 film "Beaches" and Amy Farrah Fowler on "The Big Bang Theory" in 2019: 2 wds. |
| 32% | FACTORY | 7 | Big Bang Theory Penny worked at the Cheesecake __ |
| 31% | BIALIK | 6 | Mayim who played Amy in The Big Bang Theory |
| 31% | RAJ | 3 | "The Big Bang Theory" character from India |
| 31% | RAJ | 3 | "The Big Bang Theory" astrophysicist from India |
| 31% | COOPER | 6 | Sheldon ___, character from "Big Bang Theory" who's a known neat freak |
| 31% | LEONARD | 7 | "The Big Bang Theory" friend who married Penny |
| 30% | KALEYCUOCO | 10 | "The Big Bang Theory" actress who voices Harley Quinn |
| 30% | AMY | 3 | ___ Farrah Fowler (Mayim Bialik's "The Big Bang Theory" role) |
| 30% | INDIA | 5 | Rajesh Koothrappali of "The Big Bang Theory" was from here |
| 30% | JIMPARSONS | 10 | "The Big Bang Theory" actor who narrates 44-Across (2 wds.) |
| 30% | RAJ | 3 | "The Big Bang Theory" character who was born in New Delhi |
| 29% | CHANGE | 6 | "The ___ Constant," episode of "The Big Bang Theory" where Sheldon and Amy wait to hear if they've won the Nobel Prize |
| 29% | RAJ | 3 | Only "The Big Bang Theory" friend who is unmarried when the series ends |
| 28% | MAYIMBIALIK | 11 | Former "Blossom" and "The Big Bang Theory" star who co-hosts "Jeopardy!" (2 wds,) |
| 28% | RAJ | 3 | One of five characters on "The Big Bang Theory" to appear in every episode |
| 28% | FARRAH | 6 | Amy ___ Fowler (Mayim Bialik's role on "The Big Bang Theory") |
| 28% | MAYIM | 5 | "The Big Bang Theory" actress __ Bialik who is also a scheduled 2021 "Jeopardy!" guest host |