| 100% | YURI | 4 | ___ Gagarin, first man to journey into space |
| 76% | YURI | 4 | ___ Gagarin, first human to journey into outer space |
| 68% | GAGARIN | 7 | Yuri, first man to travel into space |
| 53% | GRISSOM | 7 | First American to go into space twice |
| 53% | YURI | 4 | First man in space, ___ Gagarin |
| 52% | ALANSHEPARD | 11 | First American to travel into space (1961): 2 wds. |
| 51% | LEROY | 5 | Colonel ___ Cooper, first man to make a second orbital space flight |
| 50% | YURI | 4 | ___ Gagarin, first man in space |
| 49% | ALANSHEPARD | 11 | First American to travel into space during NASA's 1961 Freedom 7 mission |
| 45% | SALLYRIDE | 9 | First American woman to travel into space (1983): 2 wds. |
| 44% | SCHIRRA | 7 | Astronaut Wally, the first person to go into space three times |
| 44% | ALEKSEI | 7 | Leonov who was the first man to walk in space |
| 43% | ADAM | 4 | First man to encounter a barrier |
| 43% | ADAM | 4 | First man to find a barrier |
| 43% | ADAM | 4 | First man to walk the Earth? |
| 43% | ADAM | 4 | First man to walk in Eden |
| 43% | ADAM | 4 | First man to exist, mate of Eve |
| 43% | ABEL | 4 | First man to die in the Bible |
| 43% | ADAM | 4 | First man to have a mad turn |
| 42% | AGASSI | 6 | First man to achieve a Career Golden Slam |
| 42% | NADAL | 5 | First man to complete tennis's Surface Slam |
| 42% | GAGARIN | 7 | First man in space |
| 42% | YURIGAGARIN | 11 | First man in space |
| 41% | OHIO | 4 | Home of the first man to walk on the moon, the first American to orbit Earth and the first American woman to walk in space |
| 41% | AMUNDSEN | 8 | First man to go on both North and South Poles |
| 40% | ADAM | 4 | First man according to the Bible |
| 40% | WHYMPER | 7 | Edward —, first man to climb Alpine mountain the Matterhorn |
| 40% | SPUTNIK | 7 | First man-made space satellite |
| 39% | JANNINGS | 8 | Emil __, first man to win an Oscar for Best Actor |
| 39% | WEBB | 4 | Matthew —, steamship captain; first man to swim the English Channel |