| 100% | IMELDA | 6 | ___ Marcos, longtime first lady of the Philippines |
| 95% | IMELDA | 6 | ___ Marcos, longtime first lady of the Philippines with a notorious shoe collection |
| 73% | IMELDAMARCOS | 12 | First Lady of the Philippines from 1965-86 |
| 59% | RAISA | 5 | First lady of the 1980s |
| 59% | EDITH | 5 | First lady of the 1910s |
| 59% | MAMIE | 5 | First lady of the 1950s |
| 59% | BARBARABUSH | 11 | First lady of the 1990s |
| 59% | NANCYREAGAN | 11 | First lady of the 1980s |
| 59% | EVAPERON | 8 | First lady of the 1940s-'50s |
| 58% | EVAPERON | 8 | First lady of the 1940s and 1950s |
| 58% | EVAPERON | 8 | First Lady of the forties and fifties |
| 57% | RAISA | 5 | Last First Lady of the USSR |
| 57% | BILLIE | 6 | __ Holiday; First Lady of the Blues |
| 56% | MICHELLE | 8 | Obama, once First Lady of the USA |
| 56% | TODD | 4 | Mary ___ Lincoln, first lady of the 1860s |
| 56% | RAISA | 5 | ___ Gorbachev, former first lady of the Soviet Union |
| 56% | AGUINALDO | 9 | First president of the Philippines: Emilio __ |
| 55% | RAISA | 5 | Last First Lady of the U.S.S.R. |
| 54% | IMELDA | 6 | Marcos of the Philippines |
| 54% | MICHELLEOBAMA | 13 | First Lady of the United States (2009-2017) who wrote "Becoming": 2 wds. |
| 53% | MICHELLE | 8 | First name of the First Lady |
| 53% | BALL | 4 | The first lady of comedy, Lucille |
| 53% | PARKS | 5 | The First Lady of Civil Rights |
| 52% | BARBARABUSH | 11 | First Lady of the United States (1989-1993) who wrote "Millie's Book": 2 wds. |
| 52% | ABIGAIL | 7 | First name of the second first lady |
| 52% | ELLA | 4 | The First Lady of Song, to fans |
| 52% | NANCYREAGAN | 11 | First Lady of the United States (1981-1989) who wrote "To Love a Child": 2 wds. |
| 52% | JACKIEKENNEDY | 13 | Former First Lady of the United States who was born in July (2 wds.) |
| 51% | ELLA | 4 | First name of the First Lady of Song |
| 51% | ELLA | 4 | First name of the First Lady of Jazz |