| 100% | PAWTUCKET | 9 | ___ Patriot, fictional ale beloved by Peter Griffin in "Family Guy" |
| 43% | MILAKUNIS | 9 | She's the voice of Meg Griffin in Family Guy |
| 38% | QUAHOG | 6 | Fictional town in Family Guy |
| 34% | STEWIE | 6 | __ Griffin, the youngest member in Family Guy |
| 33% | STEWIE | 6 | Peter and Lois' youngest son in Family Guy |
| 31% | MEG | 3 | Peter's daughter in "Family Guy" |
| 30% | LOIS | 4 | ___ Griffin, fictional character from "Family Guy" |
| 30% | LABRADOR | 8 | Brian in Family Guy is this breed of dog |
| 30% | MILAKUNIS | 9 | She provides the voice of Meg in Family Guy |
| 30% | MEG | 3 | Character voiced by Mila Kunis in "Family Guy" |
| 29% | STEWIE | 6 | Family Guy's one-year-old baby Griffin |
| 28% | ERIC | 4 | Prince beloved by Ariel in "The Little Mermaid" |
| 28% | PETER | 5 | ___ Griffin, popular television character voiced by Seth MacFarlane in the animated sitcom "Family Guy" |
| 27% | SON | 3 | Chris or Stewie, to Peter Griffin on "Family Guy" |
| 27% | SPOONER | 7 | Street on which Family Guy's Griffin clan live |
| 27% | STEWIE | 6 | Griffin family member voiced by Seth MacFarlane |
| 27% | XXXXXXXXXX | 10 | Guy high up in the family tree |
| 27% | GLENNQUAGMIRE | 13 | Neighbor of Peter Griffin voiced by Seth MacFarlane (2 wds.) |
| 27% | EGO | 3 | Anton ___ (food critic voiced by Peter O'Toole in "Ratatouille") |
| 27% | CORLEONE | 8 | Family name in the fictional Five Families War |
| 27% | TARZAN | 6 | Fictional character raised in the jungle by apes |
| 27% | CHAN | 4 | Peter Sellers parodied him in "Murder by Death" |
| 27% | SLEDGEHAMMER | 12 | 18-Across by Peter Gabriel, in two ways |
| 27% | GRIFFINS | 8 | The ___, "Family Guy" family helmed by Peter and Lois, featuring their children Meg, Chris, and Stewie |
| 26% | MARMADUKE | 9 | Fictional dog owned by the Winslow family |
| 26% | OBOE | 4 | Woodwind played by Peter Gabriel in Genesis |
| 26% | CADFAEL | 7 | Monk-detective in novels by Ellis Peters |
| 26% | BLIND | 5 | & 14D Masque by Peter Maxwell Davies first performed in London in 1972 |
| 26% | DEADSIMPLE | 10 | 2005 novel by Peter James; first book in the Roy Grace series |
| 26% | WONKA | 5 | Fictional chocolatier played by Timothée Chalamet in 2023 |