| 100% | BILL | 4 | ___ Prady, co-creator and executive producer of CBS sitcom "The Big Bang Theory" |
| 53% | CHUCKLORRE | 10 | Creator of "Two and a Half Men" and "The Big Bang Theory," who is also the co-creator of CBS's new show "Young Sheldon": 2 wds. |
| 53% | MARK | 4 | ___ Cendrowski, director of CBS sitcom "The Big Bang Theory" |
| 47% | LORRE | 5 | "The Big Bang Theory" and "Young Sheldon" co-creator Chuck |
| 44% | NORMANLEAR | 10 | Executive producer of 32-Across and creator of the original version of the show: 2 wds. |
| 44% | RAJ | 3 | "The Big Bang Theory" chum of Sheldon and Leonard |
| 44% | AMY | 3 | "The Big Bang Theory" chum of Bernadette and Penny |
| 44% | DICKWOLF | 8 | Creator and executive producer of Law and Order |
| 43% | TAKEI | 5 | "Star Trek" actor George who has had cameos on "The Big Bang Theory" and "King of the Nerds" |
| 42% | BIALIK | 6 | The Big Bang Theory and Blossom star Mayim |
| 41% | GALECKI | 7 | Johnny —, actor who plays Leonard in US sitcom The Big Bang Theory |
| 41% | LORRE | 5 | "The Big Bang Theory" co-creator Chuck |
| 40% | GALECKI | 7 | Johnny —, actor who plays Leonard Hofstadter in US television sitcom The Big Bang Theory |
| 38% | LORRE | 5 | Chuck ___, creator of "The Big Bang Theory" |
| 38% | NEBRASKAN | 9 | State identity of Penny from The Big Bang Theory |
| 38% | LORRE | 5 | "The Big Bang Theory" creator Chuck |
| 38% | YOUNGSHELDON | 12 | "The Big Bang Theory" prequel about one of the scientists as a boy (2 wds.) |
| 37% | BIG | 3 | CBS sitcom "The ___ Bang Theory" |
| 37% | MAYIMBIALIK | 11 | Former "Blossom" and "The Big Bang Theory" star who co-hosts "Jeopardy!" (2 wds,) |
| 36% | LEMAITRE | 8 | Georges __, physicist of the Big Bang theory |
| 36% | RAJ | 3 | Pal of Sheldon and Leonard on "The Big Bang Theory" |
| 36% | AMY | 3 | Friend of Penny and Bernadette on "The Big Bang Theory" |
| 36% | SYNDROME | 8 | "The Stockholm ___," episode of "The Big Bang Theory" where Bernadette and Howard leave their kids for the first time |
| 36% | LORRE | 5 | Chuck who created "The Big Bang Theory" and "Mom" |
| 36% | CUOCO | 5 | Kaley ___, co-star of "The Big Bang Theory" |
| 36% | BAZINGA | 7 | The Big Bang Theory catchword |
| 36% | NERD | 4 | The Big Bang Theory stereotype |
| 36% | LORRE | 5 | Chuck ___, cocreator of "The Big Bang Theory" and "Two and a Half Men" |
| 36% | JIMPARSONS | 10 | Actor who portrayed Sheldon Cooper in "The Big Bang Theory," and is the narrator in "Young Sheldon": 2 wds. |
| 35% | SARA | 4 | Actress and executive producer Gilbert of “The Conners” |