| 100% | INES | 4 | ___ Rau (first openly transgender Playboy Playmate) |
| 52% | SMALL | 5 | Taylor ___, Vermont's first openly transgender legislator |
| 50% | LAYSHIA | 7 | ___ Clarendon, first openly transgender W.N.B.A. player |
| 49% | VICTORIASSECRET | 15 | Retailer that hired its first openly transgender model in 2019 |
| 48% | STU | 3 | Rasmussen who was the first openly transgender mayor in the U.S. |
| 46% | KIMPETRAS | 9 | First openly transgender woman to have a No. 1 song on the Billboard Hot 100 chart |
| 46% | LIA | 3 | ___ Thomas, first openly transgender athlete to win an NCAA Division I national championship (swimming) |
| 43% | ISIS | 4 | Actress and activist King who was the first openly transgender competitor on “America’s Next Top Model” |
| 43% | TEC | 3 | Religious org. of Rev. Cameron Partridge, first openly transgender priest to preach at Washington's Natl. Cathedral (2014) |
| 36% | SEXY | 4 | Sultry, as a Playboy Playmate |
| 35% | BARNEYFRANK | 11 | First openly gay U.S. congressman |
| 35% | SEXY | 4 | Like a Playboy Playmate |
| 35% | AIRBRUSHED | 10 | Like many Playboy Playmate photos |
| 34% | IGOR | 4 | ___ Benevenuto, first openly gay FIFA ref |
| 32% | LEO | 3 | ___ Varadkar, Ireland's first openly gay Prime Minister |
| 32% | ANA | 3 | ___ Brnabic, first openly gay Prime Minister of Serbia |
| 32% | OWEN | 4 | ___ Hurcum, the world's first openly nonbinary mayor |
| 32% | DANICAROEM | 10 | America's first openly trans elected state official |
| 30% | RACHELMADDOW | 12 | First openly lesbian anchor to host a major prime-time news program |
| 30% | MILK | 4 | Harvey who was California's first openly gay elected official |
| 30% | MILK | 4 | Harvey who was California's first openly gay public official |
| 29% | SEXIEST | 7 | Like Playboy's Playmate of the Year |
| 28% | CARL | 4 | Nassib who was the first openly gay player in an NFL game |
| 28% | SIGEP | 5 | First national fraternity to officially welcome transgender members (2014), informally |
| 27% | PLAYBOY | 7 | Magazine that featured its first transgender model in 1991 |
| 25% | NIA | 3 | ___ Nal, character from "Supergirl" who is the first transgender superhero on television |
| 24% | ELLIOT | 6 | Page who became the first openly trans man to appear on the cover of Time magazine (2021) |
| 23% | SHERYLSWOOPES | 13 | Openly gay basketballer who was the first woman to be signed by the WNBA: 2 wds. |
| 23% | WISECRACKER | 11 | William J Mann's 1998 book "___: The Life and Times of William Haines, Hollywood's First Openly Gay Star" |
| 21% | LEA | 3 | ___ DeLaria who became the first openly gay comic on a late-night talk show on "The Arsenio Hall Show" in 1993 |