| 100% | MELISSA | 7 | ___ Rauch, actress who plays Bernadette Rostenkowski-Wolowitz on "The Big Bang Theory" |
| 76% | MELISSA | 7 | Actress Rauch who played Bernadette on "The Big Bang Theory" |
| 63% | LAURIEMETCALF | 13 | "The Conners" actress who played Sheldon's mother on "The Big Bang Theory" (2 wds.) |
| 61% | KATHYBATES | 10 | "American Horror Story" actress who played Amy's mother on "The Big Bang Theory" (Abbr.) |
| 61% | KATEYSAGAL | 10 | "Sons of Anarchy" actress who played Penny's mother on "The Big Bang Theory" (2 wds.) |
| 60% | KALEYCUOCO | 10 | Actress who plays Penny on "The Big Bang Theory" (2 wds.) |
| 58% | PARSONS | 7 | Jim who plays Sheldon on The Big Bang Theory |
| 58% | WIL | 3 | Wheaton who plays himself on The Big Bang Theory |
| 54% | EMMATHOMPSON | 12 | Actress who plays the protagonist in "Nanny McPhee and the Big Bang," which is based on the "Nurse Matilda" books: 2 wds. |
| 53% | MAYIM | 5 | ___ Bialik, actress who plays Amy Farrah Fowler in "The Big Bang Theory" |
| 52% | WIL | 3 | Wheaton who played himself on "The Big Bang Theory" |
| 52% | CUOCO | 5 | Kaley who played Penny on "The Big Bang Theory" |
| 52% | HOWARD | 6 | Aerospace engineer Wolowitz played by Simon Helberg on "The Big Bang Theory" |
| 51% | JIMPARSONS | 10 | Actor who plays Sheldon on "The Big Bang Theory" (2 wds.) |
| 51% | JOHNNYGALECKI | 13 | Actor who plays Leonard on "The Big Bang Theory" (2 wds.) |
| 51% | BOB | 3 | Newhart who played Professor Proton on "The Big Bang Theory" |
| 50% | CUOCO | 5 | Kaley who played Penny on “The Big Bang Theory” |
| 50% | KUNALNAYYAR | 11 | Actor who played Raj on “The Big Bang Theory” |
| 50% | MELISSA | 7 | 'The Big Bang Theory' actress Rauch |
| 49% | JIMPARSONS | 10 | "The Big Bang Theory" actor who played Michael in "The Boys in the Band": 2 wds. |
| 48% | KALEYCUOCO | 10 | "The Big Bang Theory" actress who voices Harley Quinn |
| 47% | SIMON | 5 | ___ Helberg, actor who plays Howard Wolowitz in "The Big Bang Theory" |
| 47% | GALECKI | 7 | Johnny —, actor who plays Leonard in US sitcom The Big Bang Theory |
| 47% | HAWKING | 7 | Physicist Stephen, guested on The Big Bang Theory |
| 47% | HOWARD | 6 | ___ Wolowitz, comedic character played by Simon Helberg on the sitcom "The Big Bang Theory" |
| 47% | MAYIM | 5 | The Big Bang Theory actress Bialik |
| 47% | BIALIK | 6 | Mayim who played Amy in The Big Bang Theory |
| 47% | RAJ | 3 | Kunal Nayyar's character on The Big Bang Theory |
| 45% | MAYIM | 5 | "The Big Bang Theory" actress __ Bialik who is also a scheduled 2021 "Jeopardy!" guest host |
| 45% | MAYIMBIALIK | 11 | Actress who played young C.C. Bloom in the 1988 film "Beaches" and Amy Farrah Fowler on "The Big Bang Theory" in 2019: 2 wds. |