| 100% | HANK | 4 | ___ Schrader (DEA agent played by Dean Norris on 17-Across) |
| 78% | HANK | 4 | DEA agent Schrader played by Dean Norris on "Breaking Bad" |
| 68% | HANK | 4 | ___ Schrader ("Breaking Bad" DEA agent played by Dean Norris) |
| 63% | HANKSCHRADER | 12 | DEA agent on "Breaking Bad" played by Dean Norris: 2 wds. |
| 44% | DEREKMORGAN | 11 | Special agent played by 39-Across on 29-Across: 2 wds. |
| 41% | ARI | 3 | Agent played by Jeremy Piven on "Entourage" |
| 39% | DONALDTRUMP | 11 | Presidential candidate who has been played by 17-Across on "Saturday Night Live": 2 wds. |
| 38% | JOANCLAYTON | 11 | Character played by Tracee Ellis Ross on 17-Across: 2 wds. |
| 38% | ASHTONKUTCHER | 13 | "That '70s Show" actor who has been played by 17-Across on "Saturday Night Live": 2 wds. |
| 38% | OLEG | 4 | Russian agent played by Costa Ronin on "The Americans" |
| 36% | ARI | 3 | Agent Gold played by Jeremy Piven on "Entourage" |
| 36% | DWAYNEPRIDE | 11 | Special agent played by 19-Across: 2 wds. |
| 35% | DANA | 4 | Agent Scully played by Gillian Anderson on "The X-Files" |
| 34% | NILES | 5 | Crane brother played by David Hyde Pierce on 43-Across |
| 34% | EMO | 3 | Punk-derived music genre played by 17-Across |
| 33% | DEAN | 4 | ___ Norris, actor who played Walter White's brother-in-law Hank Schrader on "Breaking Bad" |
| 33% | UNCLEJESSE | 10 | Role played by 18-Across on "Full House": 2 wds. |
| 32% | ETHANHUNT | 9 | Agent played by Tom Cruise in Mission: Impossible |
| 32% | FLO | 3 | Progressive agent played by Stephanie Courtney |
| 32% | DRWATSON | 8 | Holmes' assistant, played by 29-Across on 47-Across: 2 wds. |
| 32% | JOSIAHBARTLET | 13 | Fictional president played by 43-Across on 18-Across (2 wds.) |
| 32% | MAXGOODWIN | 10 | Medical director played by 37-Across on 29-Across (2 wds.) |
| 32% | WILLANDGRACE | 12 | Former sitcom duo played by 31- and 17-Across: 3 wds. |
| 32% | MARTINBYRDE | 11 | Financial analyst played by 46-Across on 40-Down (2 wds.) |
| 32% | DATA | 4 | Android played by Brent Spiner on 4-Across |
| 31% | PINGLETON | 9 | Penny played by 31-Across/33-Across on NBC's "Hairspray Live!" |
| 31% | JOHNNOLAN | 9 | New LAPD cop played by 51-Across on 29-Across (2 wds.) |
| 31% | RICOTUBBS | 9 | Undercover detective played by Philip Michael Thomas on 52-Across (2 wds.) |
| 31% | CLAIREFINN | 10 | Medical officer played by Penny Johnson Jerald on 49-Across (2 wds.) |
| 31% | REID | 4 | "Criminal Minds" agent played by Matthew Gray Gubler |