| 100% | LYN | 3 | ___ St. James, first woman to be named the Indy 500 Rookie of the Year, 1992 |
| 65% | LYN | 3 | ___ St. James, first woman to win the Indianapolis 500 Rookie of the Year (1992) |
| 51% | LYN | 3 | ___ St. James, first female Indianapolis 500 Rookie of the Year |
| 48% | GRETATHUNBERG | 13 | First Swedish woman and first person born in the 21st century to be named "Time" magazine's Person of the Year (2 wds.) |
| 47% | STTERESA | 8 | First woman to be named Doctor of the Church, briefly |
| 41% | ORLANDO | 7 | ___ Magic, team where Shaquille O'Neal debuted and was named the 1993 NBA Rookie of the Year |
| 41% | LUKADONCIC | 10 | 2019 NBA Rookie of the Year who was named to the NBA All-Star team three years in a row (2 wds.) |
| 40% | PELOSI | 6 | First woman to be Speaker of the House |
| 39% | STTERESA | 8 | First woman to be made doctor of the Roman Catholic Church |
| 39% | TRINITYRODMAN | 13 | Washington Spirit forward who was named 2021 National Women's Soccer League Rookie of the Year (2 wds.) |
| 39% | CAROLEKING | 10 | "You've Got a Friend" singer/pianist who was the first woman to win a Grammy for Song of the Year (2 wds.) |
| 38% | CURIE | 5 | Last name of the first woman to win the Nobel Prize and who is credited with the theory of radioactivity |
| 38% | DANICAPATRICK | 13 | First woman to lead the Indy 500: 2 wds. |
| 38% | STEVIENICKS | 11 | First woman to be inducted twice into the Rock and Roll Hall of Fame |
| 38% | BONO | 4 | First musician to be a ''Time'' Person of the Year |
| 37% | ARIANAGRANDE | 12 | 17-Across and 39-Across singer who was named Billboard's 2018 Woman of the Year (2 wds.) |
| 37% | SARAHPALIN | 10 | In 2006, she became the first woman to be elected governor of Alaska: 2 wds. |
| 37% | SAHLE | 5 | ___-Work Zewde, Ethiopian politician who is the first woman to serve as the President of Ethiopia |
| 37% | MIA | 3 | ___ Mottley, Barbadian politician who is the first woman to serve as the Prime Minister of Barbados |
| 37% | DEVI | 4 | Bidya ___ Bhandari, Nepalese politician who is the first woman to serve as the President of Nepal |
| 37% | SUSANAMARTINEZ | 14 | In 2010, she became the first woman to be elected governor of New Mexico: 2 wds. |
| 37% | NIKKIHALEY | 10 | In 2010, she became the first woman to be elected governor of South Carolina: 2 wds. |
| 36% | FRANTARKENTON | 13 | Pro Football Hall of Fame quarterback who was the first pro athlete to host "Saturday Night Live," in 1977, two years after he was named the NFL MVP (2 wds.) |
| 36% | WADE | 4 | James ___, head coach and general manager of Chicago Sky who was named the 2022 WNBA "Executive of the Year" |
| 36% | RETTON | 6 | Gymnast Mary Lou who was the first woman to appear on the front of a Wheaties box |
| 36% | ANDRETTI | 8 | Only person to be named Driver of the Year in three different decades |
| 36% | MARIE | 5 | First name of the first woman to win a Nobel Prize |
| 36% | RUTH | 4 | First name of the second woman to serve on the Supreme Court |
| 36% | WALLIS | 6 | Simpson who was Time's first Woman of the Year |
| 36% | ANDREWWIGGINS | 13 | 2015 NBA Rookie of the Year who was the first overall pick in the 2014 NBA draft (2 wds.) |