| 100% | LYN | 3 | ___ St. James, first woman to win the Indianapolis 500 Rookie of the Year (1992) |
| 75% | LYN | 3 | ___ St. James, first woman to be named the Indy 500 Rookie of the Year, 1992 |
| 64% | LYN | 3 | ___ St. James, first female Indianapolis 500 Rookie of the Year |
| 50% | CAROLEKING | 10 | "You've Got a Friend" singer/pianist who was the first woman to win a Grammy for Song of the Year (2 wds.) |
| 49% | TOKYOJAPAN | 10 | Birthplace of 16-Across, who's the first Asian driver to win the Indianapolis 500: 2 wds. |
| 45% | ORR | 3 | First hockey player to win Sports Illustrated's Sportsman of the Year |
| 42% | EDITH | 5 | ___ Wharton, "The Age of Innocence" novelist and the first woman to win the Pulitzer Prize in Literature |
| 40% | MARIE | 5 | First name of the first woman to win a Nobel Prize |
| 40% | CURIE | 5 | First woman to win the Nobel Prize |
| 40% | CURIE | 5 | Surname of the first woman to win a Nobel prize |
| 40% | CURIE | 5 | First woman to win the Nobel Prize. Marie ___ |
| 40% | ZAHAHADID | 9 | First woman to win the Pritzker Architecture Prize |
| 39% | DANICAPATRICK | 13 | First woman to lead the Indy 500: 2 wds. |
| 39% | TONI | 4 | First name of the first Black woman to win a Nobel Prize in Literature |
| 39% | CURIE | 5 | Marie ___, first woman to win the Nobel Prize |
| 38% | ALUNSER | 7 | Oldest driver to win the Indianapolis 500 (2 wds.) |
| 38% | ONEAL | 5 | 1992-'93 NBA Rookie of the Year |
| 38% | GASOL | 5 | One of only three non-American NBA players to win Rookie of the Year |
| 38% | CARLOS | 6 | With 34-Across, Astros shortstop who won the 2015 AL Rookie of the Year Award |
| 38% | ADELE | 5 | Singer of the first James Bond movie theme song ever to win an Academy Award |
| 37% | CORBINCARROLL | 13 | Diamondbacks outfielder who won the National League Rookie of the Year Award in 2023: 2 wds. |
| 37% | JONATHANINDIA | 13 | Reds infielder who won the National League Rookie of the Year Award in 2021: 2 wds. |
| 37% | JEN | 3 | Cartoonist Sorensen who was the first woman to win the Herblock Prize |
| 37% | ZAHA | 4 | Hadid who was the first woman to win the Pritzker Architecture Prize |
| 37% | MORRISON | 8 | First Black woman to win the Nobel Prize in Literature |
| 37% | LADYNANCYASTOR | 14 | First woman to sit in the British House of Commons |
| 37% | ONEAL | 5 | NBA Rookie of the Year for 1992-93 |
| 37% | EDITH | 5 | Wharton, the first woman to win a Pulitzer |
| 37% | RYANHOWARD | 10 | Phillies first baseman who was the 2005 NL Rookie of the Year & 2006 NL MVP: 2 wds. |
| 37% | EDITH | 5 | Wharton who was the first woman to win the Pulitzer Prize for Literature |