| 100% | GAP | 3 | ___ teeth (dental feature for David Letterman and Madonna) |
| 48% | GAP | 3 | Feature of David Letterman's front teeth |
| 37% | HOST | 4 | David Letterman or Jimmy Fallon, for example |
| 36% | GAP | 3 | Letterman dental feature |
| 36% | GAYICONS | 8 | Mariah Carey and Madonna, for two |
| 36% | SATIRE | 6 | Genre for David and Amy Sedaris |
| 35% | NOSE | 4 | Notable facial feature for Cyrano and Pinocchio |
| 35% | GUMLINE | 7 | Dental margin between teeth and flesh |
| 35% | CHINS | 5 | Exaggerated facial features for Peter and Chris Griffin |
| 35% | IMPLANT | 7 | Dental __, surgical fixture for missing teeth |
| 34% | DECAY | 5 | Tooth ___ (reason for a dental filling) |
| 34% | ENO | 3 | Producer for David Bowie and U2 |
| 34% | RESTOFMYLIFE | 12 | Hit single from Ludacris, featuring Usher and David Guetta, that was included as part of the soundtrack for "Fast & Furious 6": 4 wds. |
| 33% | GAP | 3 | Dental feature of Michael Strahan and Anna Paquin |
| 33% | GAP | 3 | Dental feature of Michael Strahan and Lauren Hutton |
| 33% | OBES | 4 | Honors for David Beckham and Leona Lewis: Abbr. |
| 33% | EVITA | 5 | Role for Patti LuPone and Madonna |
| 33% | MOUTHWASH | 9 | Rinsing aid for teeth and gums |
| 33% | PARTIALS | 8 | Replacements for missing teeth in dental arches |
| 32% | EVAPERON | 8 | Musical role for Madonna and Patti LuPone |
| 32% | PRESSURE | 8 | Under __, collaboration for Queen and David Bowie |
| 32% | POETS | 5 | Elizabeth Acevedo and David Dabydeen, for two |
| 32% | ESCAPEARONI | 11 | Harry Houdini and David Blaine, for two |
| 32% | BARRACUDA | 9 | Large fish known for its teeth and aggression |
| 32% | ANIMAL | 6 | Drummer for Dr. Teeth and the Electric Mayhem |
| 32% | EDM | 3 | Music genre for David Guetta and Calvin Harris |
| 32% | BBQS | 4 | Cookouts featuring ribs, burgers, and franks, for short |
| 32% | SONS | 4 | Rocco and David, to Madonna |
| 31% | YOUNG | 5 | David —, Secretary of State for Trade and Industry from 1987-89 |
| 31% | SPOONERISM | 10 | Feature of the clues for 17-, 25-, 41- and 52-Across |