| 100% | CAROL | 5 | ___ Willick, Ross's ex-wife on "Friends" who was played by both Anita Barone and Jane Sibbett |
| 44% | REGGIE | 6 | ___ Mantle, "Riverdale" character who was played by both Ross Butler and Charles Melton |
| 40% | MORTY | 5 | ___ Seinfeld, Jerry's dad on "Seinfeld" who was played by both Phil Bruns and Barney Martin |
| 34% | ETHEL | 5 | Muggs who was played by Shannon Purser on The CW's "Riverdale" |
| 33% | STEPHENS | 8 | Darrin ___, "Bewitched" character who was played by both Dick York and Dick Sargent |
| 32% | GEORGECOSTANZA | 14 | Character who is Jerry's best friend since high school and is played by Jason Alexander on the show "Seinfeld": 2 wds. |
| 32% | MORTY | 5 | ___ Seinfeld, Jerry's father who was played by two different actors on "Seinfeld" |
| 31% | DALE | 4 | Character who was played by Jeffrey DeMunn on "The Walking Dead" |
| 31% | DWIGHTSCHRUTE | 13 | A character from "The Office" played by Rainn Wilson, who is the nemesis and eventual friend of 42a: 2 wds |
| 31% | NEWMAN | 6 | Jerry's archnemesis and neighbor played by Wayne Knight who is a recurring character on "Seinfeld" |
| 31% | ENOLA | 5 | Holmes who was played by Millie Bobby Brown in 2020 and 2022 |
| 31% | CLAIREDANES | 11 | "Homeland" actress who plays Toby Fleishman's ex-wife on "Fleishman Is in Trouble" (2 wds.) |
| 30% | NIGHT | 5 | The ___ King, "Game of Thrones" character who was played by both Richard Brake and Vladimir Furdik |
| 30% | HOOD | 4 | Robin ___, "Once Upon a Time" character who was played by both Tom Ellis and Sean Maguire |
| 30% | JANICE | 6 | Chandler's ex-girlfriend played by Maggie Wheeler who is known for her laughter in "Friends" |
| 30% | IRIS | 4 | Novelist Murdoch who was played by Kate Winslet and Judi Dench in a 2001 biopic |
| 30% | WET | 3 | The ___ Bandits, villains in "Home Alone" who are played by Joe Pesci and Daniel Stern |
| 30% | ALFIESOLOMONS | 13 | "Peaky Blinders" character, played by Tom Hardy, who ran a distillery and was seen on the show from season 2 till 4: 2 wds. |
| 30% | IRENE | 5 | ___ Adler, iconic character from the Sherlock Holmes stories who was played by Lara Pulver on screen |
| 29% | MARY | 4 | ___ Morstan, Watson's wife in the Sherlock Holmes stories who was played by Amanda Abbington on screen |
| 29% | SETHROGEN | 9 | "The Studio" actor who plays Sylvia's friend Will on "Platonic": 2 wds. |
| 29% | KELECHIWATSON | 13 | Actress Susan ___, who plays Randall's wife Beth Pearson on "This Is Us": 2 wds. |
| 29% | ANTONIATHOMAS | 13 | Actress who plays Shaun's friend and fellow resident Claire on 15-Across: 2 wds. |
| 28% | ELLIOTTGOULD | 12 | "Ocean's Eleven" actor who played Monica and Ross's father, Jack Geller, on "Friends": 2 wds. |
| 28% | SETH | 4 | ___ and Evan, friends from the film "Superbad" who are played by Jonah Hill and Michael Cera |
| 28% | LEO | 3 | Uncle ___, Jerry's relative played by Len Lesser who is a recurring character on "Seinfeld" |
| 28% | THEPENGUIN | 10 | Batman foe who’s been played by Danny DeVito and Colin Farrell |
| 28% | ADLER | 5 | Irene who was played by Rachel McAdams in 2009’s “Sherlock Holmes” |
| 28% | TAMMYS | 6 | Both of Ron Swanson's ex-wives on "Parks and Recreation" |
| 28% | SIENNAMILLER | 12 | "Live by Night" actress who plays Roger's wife Beth Ailes on "The Loudest Voice" (2 wds.) |