| 100% | DOROTHEA | 8 | __ Brooke, Middlemarch's main female character |
| 59% | HEROINE | 7 | Main female character |
| 54% | MINA | 4 | Harker, main female character in Dracula |
| 47% | MIRIAM | 6 | O. Henry Award-winning Truman Capote story, or either of its main female characters |
| 46% | NIKITA | 6 | The CW drama about a female spy (2010-2013), or the main character's first name |
| 44% | TORRANCE | 8 | Jack __, main character in S. King's The Shining |
| 42% | HERO | 4 | Novel's main character |
| 42% | CLAM | 4 | Chowder's main character? |
| 41% | LISBETH | 7 | __ Salander, Larsson's trilogy main character |
| 41% | FLIK | 4 | "A Bug's Life" main character |
| 40% | ACHILLES | 8 | Main character of Homer's The Iliad |
| 40% | JAROD | 5 | Main character of TV's "The Pretender" |
| 40% | SAMSA | 5 | Main character in Kafka's "The Metamorphosis" |
| 40% | PROSPERO | 8 | Main character of Shakespeare's The Tempest |
| 40% | OFFRED | 6 | Main character in The Handmaid's Tale |
| 40% | PROSPERO | 8 | Main character in Shakespeare's The Tempest |
| 40% | OTIS | 4 | Main character on Netflix's "Sex Education" |
| 40% | SAMSA | 5 | Main character of Kafka's Metamorphosis, Gregor __ |
| 39% | LEADINGLADY | 11 | Main female role |
| 39% | GUS | 3 | Main character in Larry McMurtry's "Lonesome Dove" |
| 39% | ARLO | 4 | Main character of Pixar's "The Good Dinosaur" |
| 39% | OLAV | 4 | Main character in Sigrid Undset's "Hestviken" tetralogy |
| 39% | PHILCOULSON | 11 | Main character on ABC's "Marvel's Agents of S.H.I.E.L.D.": 2 wds. |
| 39% | PRINCESS | 8 | Female royal title; many are Disney's characters |
| 39% | REY | 3 | The Last Jedi's central female character |
| 39% | REE | 3 | "Winter's Bone" main character ___ Dolly |
| 38% | OPHELIA | 7 | One of the only two female characters in Shakespeare's "Hamlet" |
| 38% | SWANN | 5 | Main character in Proust's "Remembrance of Things Past" |
| 38% | REE | 3 | Main character of the 2010 film "Winter's Bone" |
| 38% | VOORHEES | 8 | The surname of Friday the 13th's main character |